| Description |
1 online resource (xii, 257 pages) : illustrations |
| Series |
Progress in molecular and subcellular biology, 0079-6484 ; 44 |
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Progress in molecular and subcellular biology ; 44. 0079-6484
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| Contents |
Methods and platforms for the quantification of splice variants' expression / Laurent Bracco [and others] -- Pre-mRNA missplicing as a cause of human disease / Tatyana Novoyatleva [and others] -- Alternative splicing : therapeutic target and tool / Mariano A. Garcia-Blanco -- SR proteins as potential targets for therapy / Johann Soret, Mathieu Gabut, Jamal Tazi -- Misregulation of tau alternative splicing in neurodegeneration and dementia / Athena Andreadis -- Spinal muscular atrophy and therapeutic prospects / Brunhilde Wirth, Lars Brichta, Eric Hahnen -- Misregulation of alternative splicing causes pathogenesis in myotonic dystrophy / N. Muge Kuyumcu-Martinez, Thomas A. Cooper -- Redirecting splicing to address dystrophin mutations : molecular by-pass surgery / Stephen D. Wilton, Susan Fletcher -- Altered splicing in prelamin A-associated premature aging phenotypes / Annachiara De Sandre-Giovannoli, Nicolas Levy -- Splicing modulation as a modifier of the CFTR function / Malka Nissim-Rafinia, Batsheva Kerem |
| Summary |
Splicing of primary RNA transcript is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. This book talks about this alternate pathway |
| Analysis |
biochemie |
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biochemistry |
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celbiologie |
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cellular biology |
|
levenswetenschappen |
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life sciences |
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Biology (General) |
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Biologie (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer e-books |
| Subject |
Genetic polymorphisms.
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RNA splicing.
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Genetic regulation.
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Genetic disorders.
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Alternative Splicing
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Polymorphism, Genetic
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RNA Splicing
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Gene Expression Regulation
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Genetic Diseases, Inborn
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SCIENCE -- Life Sciences -- Molecular Biology.
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RNA splicing.
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Alternative Splicing.
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Gene expression regulation.
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Genetic Diseases, Inborn.
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Genetic polymorphisms.
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Biomédecine.
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Sciences de la vie.
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Genetic regulation
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Genetic disorders
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Genetic polymorphisms
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RNA splicing
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| Form |
Electronic book
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| Author |
Jeanteur, Ph. (Philippe)
|
| ISBN |
9783540344490 |
|
3540344497 |
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3540344489 |
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9783540344483 |
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