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Title Diffuse low-grade gliomas in adults : natural history, interaction with the brain, and new individualized therapeutic strategies / edited by Hugues Duffau
Published London : Springer, 2013

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Description 1 online resource (xviii, 502 pages) : illustrations (some color)
Contents Epidemiology and Classification -- Epidemiology of Diffuse Low-Grade Gliomas -- Histological Classification -- Is Gliomatosis Cerebri a Diffuse Low-Grade Glioma? -- Contribution of Molecular Biology to the Classification of Low-Grade Diffuse Glioma -- Basic Science and Experimental Research in DLGG -- Cellular Origin of Grade II Gliomas -- Deciphering the Molecular and Cellular Basis for Dissemination of Diffuse Low-Grade Gliomas -- The Molecular Biology of Diffuse Low-Grade Gliomas -- Proteomic Studies in Low-Grade Gliomas: What Have They Informed About Pathophysiology? -- Human Low-Grade Glioma Cultures -- Animal Models for Low-Grade Gliomas -- Clinical Aspects and Diagnostic Imaging -- Clinical Presentation in Diffuse Low-Grade Gliomas -- Epilepsy in Diffuse Low-Grade Gliomas -- Quality of Life in Low-Grade Gliomas -- Metabolic-Oncological MR Imaging of Diffuse Low-Grade Glioma: A Dynamic Approach -- Positron Emission Tomography in Diffuse Low-Grade Gliomas -- Dynamics of DLGG and Clinical Implications -- Natural History and Spontaneous Prognostic Factors -- Natural History and Spontaneous Prognostic Factors -- Functional Assessment and Interaction with the Brain -- Language and Other Cognitive Evaluations -- Functional MR and Diffusion MR Imaging in Diffuse Low-Grade Gliomas
Summary The biology, behavior and management of diffuse low-grade gliomas (DLGG) in adults have been matters of controversy for many decades. However, recent technical and conceptual advances in genetics, imaging and treatments have paved the way towards individualized management. In addition, advancing knowledge of brain processing means that it is possible to take into consideration the interaction between the disease (low-grade glioma) and the host (the brain) and thus to modulate the therapeutic strategies with the goal to increase the median survival as well as to improve the quality of life. Diffuse Low-Grade Gliomas in Adults: Natural History, Interaction with the Brain, and New Individualized Therapeutic Strategies presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualized therapy for this kind of tumor. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book. This book uniquely focuses on addressing diffuse low-grade gliomas in adults and is a valuable resource for medical oncologists, neuro-oncologists and neurologists
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Gliomas -- Treatment
Gliomas -- Imaging
Adulthood.
Diagnostic imaging.
Oncology.
Human beings.
Adult
Humans
Diagnostic Imaging
Glioma -- therapy
Medical Oncology
Neoplasms
adulthood.
adults (people)
Homo sapiens (species)
HEALTH & FITNESS -- Diseases -- Cancer.
MEDICAL -- Oncology.
Médecine.
Medicine
Nervous system -- Radiography
Neurology
Oncology
Form Electronic book
Author Duffau, Hugues.
ISBN 9781447122135
1447122135
9781447122128
1447122127