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Title Recent advances in IgA nephropathy / editor, Kar Neng Lai
Published Hackensack, NJ : World Scientific, 2009


Description 1 online resource (xx, 419 pages) : illustrations
Contents 1. IgA nephropathy : discovery of a distinct glomerular disorder / Keng Thye Woo, Richard J. Glassock and Kar Neng Lai -- 2. Epidemiology and ancestral difference / Francesco P. Schena and Francesco Pesce -- 3. Genetic contribution to IgA nephropathy / Patrick H. Maxwell and Yiming Wang -- 4. Histopathology, immunofluorescence and ultrastructural examination / Fernand M. Lai -- 5. Tubulointerstitial injury in IgA nephropathy / Joris J. Roelofs and Sandrine Florquin -- 6. Podocyte pathology / Kar Neng Lai and Joseph C.K. Leung -- 7. Clinicopathologic findings / Bruce A. Julian and Robert J. Wyatt -- 8. Clinical course of primary IgA nephropathy / Franc̮ois C. Berthoux and Hesham Mohey -- 9. Special clinical syndromes / Judit Nagy and Tibor Kovács -- 10. IgA nephropathy in children / Ronald J. Hogg -- 11. Recurrent IgA nephropathy in transplant / Bo Ying Choy and Kar Neng Lai -- 12. IgA molecule / Jan-Willem Eijgenraam, Mahamed R. Daha and Cees van Kooten -- 13. IgA immune-complex / Jan Novak and Jiri Mestecky -- 14. B and T lymphocytes / Abdalla Rifai and Ann Chen -- 15. IgA receptors and mesangial IgA deposition / Ivan C. Moura and Renato C. Monteiro -- 16. Antigen-dependent mechanism of IgA nephropathy / Yasuhiko Tomino and Yoshio Shimizu -- 17. Complement activation / Sydney C.W. Tang and Kar Neng Lai -- 18. Cytokines and growth factors / Jürgen Floege and Tammo Ostendorf -- 19. Monocytes and macrophages / Yohei Ikezumi and David J. Nikolic-Paterson -- 20. Renin-angiotensin system / Kar Neng Lai and Joseph C.K. Leung -- 21. Corticosteroids / Claudio Pozzi and Lucia Del Vecchio -- 22. Treatment for IgA nephropathy : renin-angiotensin blockade / Rosanna Coppo and Licia Peruzzi -- 23. Other immunomodulatory agents / Sydney C.W. Tang and Kar Neng Lai -- 24. Other non-immunomodulatory agents / Jonathan Barratt and John Feehally -- 25. Treatment of IgA nephropathy : tonsillectomy / Osamu Hotta -- 26. Experimental model of IgA nephropathy / Yusuke Suzuki and Yasuhiko Tomino -- 27. Future prospects for IgA nephropathy / Richard J. Glassock
Summary IgA nephropathy is the most common primary glomerulonephritis in developed countries. The primary defect lies in the abnormalities of the IgA molecule. The disease affects all ages, mainly in the young adults, and may recur in a transplanted kidney. This outstanding volume provides a comprehensive overview of the advances in this disease over the last ten years. It covers the genetics, epidemiology, clinicopathological features, pathogenesis, prognostic mechanisms, and treatment of this unique disease. Twenty-seven chapters are written by 43 experts from 13 countries; these experts have been providing forefront scientific findings to the scientific community for the last 20 years. The book covers all clinical, pathological and molecular aspects of IgA nephropathy. This is an essential source of reference for nephrologists, internists, pathologists, and molecular biologists. It is also suitable reading for graduate students or research scientists in the field of kidney diseases
Bibliography Includes bibliographical references and index
Notes Print version record
Subject IgA glomerulonephritis.
Glomerulonephritis, IGA
MEDICAL -- Nephrology.
IgA glomerulonephritis
Urology & Nephrology.
Health & Biological Sciences.
Form Electronic book
Author Lai, Kar Neng.
LC no. 2009289025
ISBN 9789812835871