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Title Biochemical approaches for glutamatergic neurotransmission / editors Sandrine Parrot, Luc Denoroy
Published New York : Humana Press imprint is published by Springer Nature, [2017]


Description 1 online resource (xii, 565 pages) : illustrations (chiefly color)
Series Neuromethods, 1940-6045 ; volume 130
Neuromethods ; 130. 0893-2336
Contents Identification of glutamatergic neurons / Shiliang Zhang and Marisela Morales -- Single nanoparticle tracking : a method for investigating the surface dynamics of glutamate receptors / Julien Dupuis, François Maingret, and Laurent Groc -- Positron emission tomography of metabotropic glutamate receptors / Selena Milicevic Sephton -- NMR spectroscopy of brain glutamate function / Jun Shen -- Imaging glutamate with genetically encoded fluorescent sensors / Gerard J. Broussard, Elizabeth K. Unger, Ruqiang Liang, Brian P. McGrew, and Lin Tian -- Measurement of astrocytic glutamate release using genetically encoded probe combined with TIRF microscopy / Fuyuko Takata-Tsuji, Naura Choulnamountri, Christophe Place, and Olivier Pascual -- Drugs to alter extracellular concentration of glutamate : modulators of glutamate uptake systems / Andréia Cristina Karklin Fontana -- Drugs to tune up glutamatergic systems : modulators of glutamate metabotropic receptors / Kathy Sengmany and Karen J. Gregory -- Glutamatergic synthesis, recycling, and receptor pharmacology at Drosophila and Crustacean neuromuscular junctions / Joshua S. Titlow and Robin L. Cooper -- Optical control of glutamate receptors of the NMDA-kind in mammalian neurons, with the use of photoswitchable ligands / Shai Berlin and Ehud Y. Isacoff -- In vivo electrochemical studies of optogenetic control of glutamate signaling measured using enzyme-based ceramic microelectrode arrays / Jason J. Burmeister, Francois Pomerleau, Jorge E. Quintero, Peter Huettl, Yi Ai, Johan Jakobsson, Martin Lundblad, Andreas Heuer, John T. Slevin, and Greg A. Gerhardt -- Separation-based sensors using microchip electrophoresis with microdialysis for monitoring glutamate and other bioactive amines / Nathan Oborny, Michael Hogard, and Susan M. Lunte -- Brain glutamate monitoring by microdialysis and separation methods with a special focus on capillary electrophoresis with laser-induced fluorescence detection / Luc Denoroy and Sandrine Parrot -- In vivo determination of glutamate uptake by brain microdialysis / Sandrine Parrot, Monique Touret, and Luc Denoroy -- Enzymes of glutamate system / Irina S. Boksha, Olga K. Savushkina, Elena B. Tereshkina, Tatyana A. Prokhorova, and Elizabeta B. Mukaetova-Ladinska -- Glutamatergic system as potential clinical biomarkers for blood and cerebrospinal fluid monitoring / Kenji Hashimoto -- Clinical CNS microdialysis of glutamate with a special methodological focus on human spinal cord / Bernard Renaud, Luc Denoroy, Delphine Collin-Chavagnac, Patrick Mertens, and Sandrine Parrot
Summary "This volume presents techniques and recent developments in biochemical approaches to study glutamatergic neurotransmission. This book contains detailed discussions on tracing neuronal pathways, functional or spectroscopic imaging, optogenetic or pharmacological tools, and extracellular neurochemistry in experimental clinical models. The chapters cover topics such as: identification of glutamatergic neurons in a discrete brain area, tools to study dynamics of single ionotropic receptors, in vivo extracellular glutamate monitoring in preclinical research using biosensors, capillary electrophoresis and liquid chromatography, and potential brain glutamatergic clinical biomarkers in biofluids and tissues. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory"--Publisher's description
Bibliography Includes bibliographical references and index
Notes Online resource; title from electronic title page (SpringerLink, viewed September 26, 2017)
Subject Glutamic acid -- Laboratory manuals
Neurotransmitters -- Laboratory manuals
Neural transmission.
Laboratory Manuals
Glutamic Acid -- metabolism
Synaptic Transmission
Excitatory Amino Acid Agents
Medical -- Neuroscience.
Neural transmission
Glutamic acid
Genre/Form Laboratory manuals
Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Parrot, Sandrine, editor
Denoroy, Luc, editor
ISBN 9781493972289