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Title Bone marrow transplantation across major genetic barriers / editors, Yair Reisner, Massimo F. Martelli
Published Hackensack, NJ : World Scientific, 2010

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Description 1 online resource (xi, 479 pages) : illustrations
Contents The haploidentical option for high-risk haematological malignancies / Franco Aversa, Yair Reisner, and Massimo F. Martelli -- Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning / Wolfgang A. Bethge -- The challenge in hematopoietic stem cell transplantation : shortening the immunodeficiency period / Liliane Dal Cortivo [and others] -- Hematopoietic stem cell transplantation across genetic barriers using a nonmyeloablative conditioning regimen -- / Liang-Piu Koh, David A. Rizzieri, and Nelson J. Chao -- Adoptive immunotherapy for prophylaxis and therapy of infectious complications after allogeneic hematopoietic stem cell transplantation / Markus Kapp, Hermann Einsele, and Götz Ulrich Grigoleit -- Alloreactive T cells for the treatment of leukemia / J.H. Frederik Falkenburg -- Alloanergization in haploidentical hematopoietic stem cell transplantation / Jeff K. Davies, Lee M. Nadler, and Eva C. Guinan -- The role of the thymus in hematopoietic stem cell transplantation / Werner Krenger and Georg A. Holländer -- A revolutionary BMT method / Susumu Ikehara -- Treatment of adenovirus infection after haploidentical stem cell transplantation in children / Tobias Feuchtinger, Rupert Handgretinger, and Peter Lang -- Mobilization of hematopoietic stem and progenitor cells / Kfir Lapid [and others] -- Regulatory T cell therapy for immunomodulation after allogeneic hematopoietic cell transplantation / Robert Zeiser and Robert S. Negrin -- Immune reconstitution after haploidentical hematopoietic stem cell transplantation / Ami Shah [and others] -- Human T cell differentiation : new techniques, old challenges / Jean Plum [and others] -- Crossing HLA barriers by "megadose" stem cell transplants / Yair Reisner, Massimo F. Martelli, and Esther Bachar-Lustig -- Pathogen-induced immune regulation in transplantation / Luigina Romani -- Optimising adoptive T cell therapy following allogeneic hematopoietic stem cell transplantation / Sara Ghorashian [and others] -- Hematopoietic cell transplantation for induction of transplantation tolerance : from animal models to clinical trials / Megan Sykes -- Unmanipulated HLA-mismatched/haploidentical blood and marrow hematopoietic stem cell transplantation / Xiao-Jun Huang -- Deploying natural killer cell allotherapy in the setting of HLA-haplotype-mismatched hematopoietic stem cell transplantation / Andrea Velardi [and others]
Summary The importance of bone marrow transplantation for patients who do not have a matched sibling donor cannot be overestimated. This subject has always been in the public domain, accentuated by dramatic appeals, from time to time, to search for matched volunteer donors in the public at large. Unfortunately, the availability of such donors is limited, due to the remarkable genetic diversity of humans. Thus, although registries of such volunteers now include more than seven million individuals, we still face the problem of finding a matched donor for about 30 per cent of patients in need. To address
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Bone marrow -- Transplantation.
Hematopoietic stem cells.
Graft versus host disease -- Prevention
Graft rejection -- Prevention
Human immunogenetics.
Human genetics -- Variation.
Bone Marrow Transplantation -- methods
Genetic Variation
HLA Antigens -- genetics
Hematopoietic Stem Cell Transplantation -- methods
Hematopoietic Stem Cells -- immunology
T-Lymphocytes -- immunology
Bone Marrow Transplantation
Hematopoietic Stem Cells
MEDICAL -- Surgery -- General.
Human genetics -- Variation
Bone marrow -- Transplantation
Graft rejection -- Prevention
Graft versus host disease -- Prevention
Hematopoietic stem cells
Human immunogenetics
Genre/Form Electronic books
Form Electronic book
Author Reisner, Yair
Martelli, M. F
ISBN 9789814271271
9814271276
1283143666
9781283143660
9786613143662
6613143669