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Title Recombination and meiosis : crossing-over and disjunction / volume editors, Richard Egel, Dirk-Henner Lankenau
Published Berlin ; New York : Springer, ©2008

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Description 1 online resource (xiv, 365 pages) : illustrations
Series Genome dynamics and stability, 1861-3373 ; 2
Genome dynamics and stability ; 2. 1861-3373
Contents Meiotic Crossing-Over and Disjunction: Overt and Hidden Layers of Description and Control -- Chromatid Cores in Meiotic Chromosome Structure and Segregation -- Sister Chromatid Cohesion and Centromere Organization in Meiosis -- Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis -- Synapsis, Double-Strand Breaks, and Domains of Crossover Control in Drosophila Females -- Synaptic and Recombination Nodules in Mammals: Structural Continuity with Shifting Protein Composition -- Human Recombination Hotspots: Before and After the HapMap Project -- Meiotic Nondisjunction--The Major Cause of Trisomy 21 -- Meiosis in Arabidopis thaliana: Recombination, Chromosome Organization and Meiotic Progression -- Modified Cell Cycle Regulation in Meiosis
Summary "Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II - reducing chromosome number from the diploid level to a haploid genome, reshuffling the homologous chromosomes by their centromeres, and recombining chromosome arms by crossing-over. In animals, including humans, all this happens during the germ cell formation of eggs and sperm. Due to the reign of meiosis, no child is a true genetic copy of either parent. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. The current book addresses these processes and mechanisms in multicellular eukaryotes, such as Drosophila, Anibidopsis, mice and humans. The pioneering model systems of yeasts, as well as evolutionary aspects, will be addressed in a forthcoming volume."--Jacket
Bibliography Includes bibliographical references and index
Notes English
Print version record
In Springer e-books
Subject Genetic recombination.
Grossing over (Genetics)
Meiosis.
Recombination, Genetic
Meiosis
Biomédecine.
Sciences de la vie.
Genetic recombination
Meiosis
Form Electronic book
Author Egel, Richard, 1942-
Lankenau, Dirk-Henner
ISBN 9783540753735
3540753737
9783540753711
3540753710
9786611355432
661135543X