Description |
1 online resource (ix, 438 pages) : illustrations (some color) |
Contents |
Cover; Contents; Foreword; Epidemiology and Causes of Drug Hypersensitivity; Epidemiology and Causes of Severe Cutaneous Adverse Reactions to Drugs; Chemical-Induced Contact Hypersensitivity in the Mouse Model; Lessons from Nickel Hypersensitivity: Structural Findings; Drugs as Haptens, Antigens, and Immunogens; The p-i Concept: Evidence and Implications; Tolerance Mechanisms to Small Molecular Compounds; HIV and Drug Hypersensitivity; Abacavir Hypersensitivity; Genetics of Severe Drug Hypersensitivity Reactions in Han Chinese; Nevirapine Hypersensitivity |
Summary |
Drug hypersensitivities are immune-mediated reactions characterized by exanthems, fever and internal organ involvement. They represent a challenging field of research: many different drugs can induce a variety of clinical symptoms through multiple mechanisms of drug-host interaction, many of which are poorly understood. This is the first book to approach the phenomenon of drug hypersensitivity in a comprehensive manner. Besides epidemiological aspects, it addresses the immunological mechanisms underlying these complicated reactions which go far beyond the IgE-mediated drug allergies also consi |
Bibliography |
Includes bibliographical references and indexes |
Notes |
Print version record |
Subject |
Drug allergy.
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Drug Hypersensitivity
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MEDICAL -- Immunology.
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HEALTH & FITNESS -- Allergies.
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HEALTH & FITNESS -- Diseases -- Immune System.
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Drug allergy
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Geneesmiddelen.
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Overgevoeligheid.
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Arzneimittelallergie -- Aufsatzsammlung.
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Form |
Electronic book
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Author |
Pichler, Werner J., 1949-
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ISBN |
9781435634046 |
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1435634047 |
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9783318014549 |
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3318014540 |
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