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Book Cover

Title HIV glycans in infection and immunity / Ralph Pantophlet, editor
Published New York, NY : Springer, 2014


Description 1 online resource (xii, 217 pages) : illustrations (some color)
Contents HIV Glycomics and Glycoproteomics / Camille Bonomelli, Max Crispin, Chris N. Scanlan and Katie J. Doores -- Innate Recognition of HIV-1 Glycans: Implications for Infection, Transmission, and Immunity / Angelic M.G. van der Aar, Sonja I. Gringhuis and Teunis B.H. Geijtenbeek -- The Influence of HIV Envelope Glycosylation on Adaptive Immune Response / Catarina E. Hioe, Rajnish Kumar and Shiu-Lok Hu -- Role of HIV Glycans in Transmission and Immune Escape / Penny L. Moore, Megan K. Murphy and Cynthia A. Derdeyn -- Molecular Recognition of HIV Glycans by Antibodies / Leopold Kong, Robyn L. Stanfield and Ian A. Wilson -- Anti-Carbohydrate HIV Vaccine Design / Lai-Xi Wang, Paolo Costantino, Yu Geng and Hong Zhang -- Lectins as HIV Microbicides / Leonardus M.I. Koharudin, Angela M. Gronenborn
Role of HIV glycans in virus transmission -- Antigenicity of HIV glycans in vivo and in vitro -- HIV glycans as immunogens
Summary Glycosylation is a common and extremely important modification in biological molecules, particularly of proteins. HIV Glycans in Infection and Protein provides an overview of the roles of glycans in the transmission/infection, antigenicity, and immunogenicity of HIV and the HIV envelope glycoprotein. It explores recent advances in the understanding of the impact of HIV glycans in infection and their promise for immunological and therapeutic intervention. Novel collaborations between glycobiologists and immunologists in recent years have led to key advances in the understanding of HIV glycans. These cross-disciplinary endeavors, their achievements and their impact on the field are all addressed, herein
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (SpringerLink, viewed November 4, 2013)
Subject Glycoproteins.
HIV (Viruses)
HIV Envelope Protein gp120
SCIENCE -- Life Sciences -- Biochemistry.
HIV (Viruses)
Form Electronic book
Author Pantophlet, Ralph, editor
ISBN 9781461488729