| Description |
1 online resource (xii, 217 pages) : illustrations (some color) |
| Contents |
HIV Glycomics and Glycoproteomics / Camille Bonomelli, Max Crispin, Chris N. Scanlan and Katie J. Doores -- Innate Recognition of HIV-1 Glycans: Implications for Infection, Transmission, and Immunity / Angelic M.G. van der Aar, Sonja I. Gringhuis and Teunis B.H. Geijtenbeek -- The Influence of HIV Envelope Glycosylation on Adaptive Immune Response / Catarina E. Hioe, Rajnish Kumar and Shiu-Lok Hu -- Role of HIV Glycans in Transmission and Immune Escape / Penny L. Moore, Megan K. Murphy and Cynthia A. Derdeyn -- Molecular Recognition of HIV Glycans by Antibodies / Leopold Kong, Robyn L. Stanfield and Ian A. Wilson -- Anti-Carbohydrate HIV Vaccine Design / Lai-Xi Wang, Paolo Costantino, Yu Geng and Hong Zhang -- Lectins as HIV Microbicides / Leonardus M.I. Koharudin, Angela M. Gronenborn |
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Role of HIV glycans in virus transmission -- Antigenicity of HIV glycans in vivo and in vitro -- HIV glycans as immunogens |
| Summary |
Glycosylation is a common and extremely important modification in biological molecules, particularly of proteins. HIV Glycans in Infection and Protein provides an overview of the roles of glycans in the transmission/infection, antigenicity, and immunogenicity of HIV and the HIV envelope glycoprotein. It explores recent advances in the understanding of the impact of HIV glycans in infection and their promise for immunological and therapeutic intervention. Novel collaborations between glycobiologists and immunologists in recent years have led to key advances in the understanding of HIV glycans. These cross-disciplinary endeavors, their achievements and their impact on the field are all addressed, herein |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed November 4, 2013) |
| Subject |
Glycoproteins.
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Glycosylation.
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HIV (Viruses)
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HIV Envelope Protein gp120
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Glycosylation
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HIV
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SCIENCE -- Life Sciences -- Biochemistry.
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Glycoproteins
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Glycosylation
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HIV (Viruses)
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| Form |
Electronic book
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| Author |
Pantophlet, Ralph, editor
|
| ISBN |
9781461488729 |
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1461488729 |
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