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Title Diagnostic pediatric hematopathology / edited by Maria Proytcheva
Published Cambridge ; New York : Cambridge University Press, 2011
Online access available from:
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Description 1 online resource (xi, 577 pages) : illustrations (chiefly color)
Contents Cover; Diagnostic Pediatric Hematopathology; Title; Copyright; Dedication; Contents; Contributors; Acknowledgements; Introduction; Section 1: General and non-neoplastic hematopathology; Chapter 1: Hematologic values in the healthy fetus, neonate, and child; Developmental hematopoiesis: a general view; Composition of fetal blood; Hematologic values in term neonates and infants; Hematologic values in small-for-gestational-age (SGA) term newborns; Hematologic values in preterm neonates; Hematologic values during early childhood and in older children
Preanalytical issues related to pediatric blood samplesLimited blood availability; Effect of blood sampling site on the hematology test results; Effect of exertion and violent crying on the white blood cell count; Other preanalytical factors affecting hematologic test results in neonates; Analytical issues related to pediatric blood samples; Interpretation of hematologic test results in children; Other factors affecting neonatal testing; Chapter 2: Normal bone marrow; Ontogeny of the hematopoietic system; Postnatal bone marrow; Age-specific differences in the bone marrow
Bone marrow examination in childrenReferences; Chapter 3: Disorders of erythrocyte production: Nutritional deficiencies, iron deficient, and sideroblastic anemia; Introduction; Iron; Dietary iron; Iron transport; Iron uptake from the intestine; Iron uptake from the plasma; Iron storage; Iron regulation; Hemoglobin synthesis; Age and iron needs; Iron in the first year; Iron in the diet; Assessment of iron status; Ferritin; Serum iron and transferrin; Zinc protoporphyrin; Soluble transferrin receptor; Treatment of iron deficiency; Vitamin B12; Role in the body; Dietary vitamin B12
Vitamin B12 absorption and metabolismVitamin B12 deficiency; Maternal vitamin B12 deficiency; Inherited disorders of transport and absorption of vitamin B12; Inborn errors of metabolism; Methylmalonyl-CoA mutase deficiency; Adenosylcobalamin deficiency; Methylcobalamin deficiency; Combined deficiencies; Acquired vitamin B12 deficiency; Assessment; Treatment; Folate; Role in the body; Dietary folate and folic acid; Folate absorption and metabolism; Folate deficiency; Pregnancy; Malabsorption; Increased utilization of folate; Drugs; Inherited disorders of transport and metabolism; Assessment
TreatmentSideroblastic anemia; References; Chapter 4: Disorders of hemoglobin synthesis: Thalassemias and structural hemoglobinopathies; Normal hemoglobins; Structure and function of hemoglobin; Genetics and transcription control of hemoglobin; Disorders of hemoglobin synthesis; Overview; Population genetics; Thalassemias; Alpha-thalassemias; Beta-thalassemias; Delta-beta-thalassemias; Structural hemoglobinopathies; Hemoglobin S; Hemoglobin C, hemoglobin D, and other rare hemoglobinopathies; Interactions of structural hemoglobinopathies with thalassemias; Laboratory evaluation; Introduction
Summary An accurate and up-to-date guide to the pathologic diagnosis of benign and malignant hematologic disorders of childhood
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Pediatric hematology.
Blood -- Diseases -- Diagnosis.
Children -- Diseases -- Diagnosis.
Hematologic Diseases -- pathology
Hematologic Neoplasms -- pathology
children (people by age group)
MEDICAL -- Pediatrics.
HEALTH & FITNESS -- Children's Health.
Blood -- Diseases -- Diagnosis
Children -- Diseases -- Diagnosis
Pediatric hematology
Form Electronic book
Author Proytcheva, Maria
ISBN 9780511919091