| Description |
xix, 221 leaves : illustrations ; 30 cm |
| Summary |
Ikaros-related transcription factors are essential for adaptive immunity. Evolutionary analysis suggested derivation from a precursor similar to the 'atypical' Pegasus protein, and possibly related to invertebrate Hunchback. Pegasus was shown to regulate neural, gut and blood cell development in zebrafish, with Ikaros identified as one of several potential gene targets |
| Notes |
Submitted to the School of Medicine of the Faculty of Health, Medicine, Nursing and Behavioural Sciences, Deakin University |
|
Thesis (Ph.D.)--Deakin University, Victoria, 2010 |
| Bibliography |
Includes bibliographical references (leaves 176-204) |
| Subject |
Hematopoiesis -- Genetic aspects.
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Immune response -- Regulation -- Genetic aspects.
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Transcription factors.
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| Genre/Form |
Academic theses.
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| Author |
Deakin University. Faculty of Health, Medicine, Nursing and Behavioural Sciences
|
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Deakin University. School of Medicine
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