Limit search to available items
Book Cover

Title Molecular mechanisms of parasite invasion / edited by Barbara A. Burleigh, Dominique Soldati-Favre
Published Austin, Tex. : Landes Bioscience ; New York : Springer Science+Business Media, ©2008


Description 1 online resource (xx, 237 pages) : illustrations (some color)
Series Subcellular biochemistry ; v. 47
Sub-cellular biochemistry ; v. 47.
Contents Current and emerging approaches to studying invasion in apicomplexan parasites / Jeffrey Mital and Gary E. Ward -- Microneme proteins in apicomplexans / Vern B. Carruthers and Fiona M. Tomley -- Erythrocyte invasion by plasmodium falciparum: multiple ligand-receptor interactions and phenotypic switching / Manoj T. Duraisingh [and others] -- Role of the gp85/trans-sialidase superfamily of glycoproteins in the interaction of trypanosoma cruzi with host structures / Maria Jølia M. Alves and Walter Colli -- Calcium regulation and signaling in apicomplexan parasites / Kisaburo Nagamune [and others] -- Trypanosoma cruzi: parasite and host cell signaling during the invasion process / Nobuko Yoshida and Mauro Cortez -- Host cell actin remodeling in response to cryptosporidium / Steven P. O'Hara [and others] -- Host cell actin remodeling in response to trypanosoma cruzi: trypomastigote versus amastigote entry / Renato A. Mortara [and others] -- Actin/myosin-based gliding motility in apicomplexan parasites / Kai Matuschewski and Herwig Schøler -- Roles of proteases during invasion and egress by plasmodium and toxoplasma / Timothy J. Dowse [and others] -- Roles of naturally occurring protease inhibitors in the modulation of host cell signaling and cellular invasion by trypanosoma cruzi / Julio Scharfstein and Ana Paula C.A. Lima -- Biogenesis of and activities at the toxoplasma gondii parasitophorous vacuole membrane / Anthony P. Sinai
The role of host cell lysosomes in trypanosoma cruzi invasion / G. Adam Mott and Barbara A. Burleigh -- Leishmania invasion and phagosome biogenesis / Robert Lodge and Albert Descoteaux -- Plasmodium sporozoite passage across the sinusoidal cell layer / Ute Frevert [and others] -- Transepithelial migration by toxoplasma / Antonio Barragan and Niclas Hitziger -- The microsporidian polar tube and its role in invasion / Frederic Delbac and Valerie Polonais -- Intestinal invasion by entamoeba histolytica / Shahram Solaymani-Mohammadi and William A. Petri, Jr
Summary All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens-not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells
Bibliography Includes bibliographical references and index
Subject Molecular parasitology.
Host-parasite relationships.
Trypanosoma cruzi -- physiology
Host-Parasite Interactions -- physiology
Actins -- physiology
Apicomplexa -- physiology
Protease Inhibitors -- metabolism
Host-Parasite Interactions
MEDICAL -- Parasitology.
Host-parasite relationships.
Host-Parasite Interactions -- physiology.
Trypanosoma cruzi -- physiology.
Actins -- physiology.
Apicomplexa -- physiology.
Protease Inhibitors -- metabolism.
Molecular parasitology.
Sciences de la vie.
Host-parasite relationships
Molecular parasitology
Form Electronic book
Author Burleigh, Barbara A.
Soldati, Dominique.
ISBN 9780387782669