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Title The human hypothalamus. Middle and posterior region / volume editors Dick F. Swaab, Felix Kreier, Paul J. Lucassen, Ahmad Salehi, and Ruud M. Buijs
Published Amsterdam, Netherlands : Elsevier, [2021]

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Description 1 online resource (xxxviii, 520 pages) illustration (some color)
illustrations.
Series Handbook of clinical neurology ; volume 180, 3rd series
Handbook of clinical neurology ; 3rd ser., v. 180. http://id.loc.gov/resources/hubs/0943a8f0-bf1d-8ed7-8951-3c55e037c598
Contents Intro -- The Human Hypothalamus: Middle and Posterior Region -- Copyright -- Handbook of Clinical Neurology 3rd Series -- Foreword -- Preface -- The HCN volumes on the Human Hypothalamus -- The hypothalamus: Arbitrary borders -- References -- Contributors -- Contents -- Contents of related volumes -- Chapter 1: Introduction: The middle and posterior hypothalamus -- Section 6#: Supraoptic and Paraventricular Nucleus: More than a Neuroendocrine System -- Section 7: Zona Incerta -- Section 8: Ventromedial Nucleus and Dorsomedial Nucleus -- Section 9: Circumventricular Organs of the Hypothalamus -- Section 10: Lateral Tuberal Nucleus -- Section 11: Lateral Hypothalamic Area, Perifornical Area -- Section 12: Tuberomamillary Complex -- Section 13: Subthalamic Nucleus -- Section 14: Corpora Mamillaria, Fornix, and Mamillothalamic Tract -- References -- Section 6: Supraoptic and paraventricular nucleus more than a neuroendocrine system -- Chapter 2: Vasopressin and oxytocin beyond the pituitary in the human brain -- Accessory Magnocellular Neuroendocrine System of the Hypothalamus -- Vasopressin- and Oxytocin-Containing Neurons and Fibers in the Forebrain -- Vasopressin and Oxytocin Are Involved in Motivated Social Behavior -- Localization of the Neurons Involved in Behavioral and Physiological Functions and Targeted by Vasopressinergic and Oxytociner -- Forebrain -- Brainstem and spinal cord -- Vasopressin in the Suprachiasmatic Nucleus -- Vasotocin, Vasopressin, and Oxytocin in the Mammalian Pineal Gland -- Conclusions -- References -- Chapter 3: Central and peripheral release of oxytocin: Relevance of neuroendocrine and neurotransmitter actions for physi ... -- Introduction -- Organization of the Hypothalamic-Neurohypophyseal (HHNS) System -- Parvocellular Oxytocin Neurons of the Hypothalamus: Master Cells Arranging the HHNS Activity?
Heterogeneity of Oxytocin Neurons -- Synaptic vs Nonsynaptic Oxytocin Release -- Intracellular Oxytocin Receptor Signaling -- Oxytocin System in Monkeys and Human -- Oxytocin in Human Health -- Perspectives -- Acknowledgments -- References -- Chapter 4: Organization of the neuroendocrine and autonomic hypothalamic paraventricular nucleus -- Introduction1 -- Hypothalamic Integration of Time of Day -- Control of the Daily Rhythm in HPA axis Activity -- Control of the Daily Rhythm in HPT Axis Activity -- Control of the Daily Rhythm in Prolactin Release -- Control of the Daily Rhythm in Pineal Melatonin Release -- Control of the Daily Rhythm in Plasma Glucose Concentrations -- Control of the Daily Rhythm in Feeding-Induced Insulin Responses -- Multiple Subpopulations of Preautonomic Neurons -- Future Perspective -- References -- Chapter 5: Sex differences of oxytocin and vasopressin in social behaviors -- Introduction -- Models and Interventions -- Sexually Dimorphic Influences of OT on Social Cognition -- Partner preference and sexual orientation -- Memory modulation -- Emotion regulation -- Trust-related behaviors -- Sexually Dimorphic Influences of VP on Social Cognition -- Effects of OT and VP on Social Cognition of Women During Pregnancy, Birth, and Lactation -- OT in peripartum period -- VP in peripartum period -- Discussion -- References -- Chapter 6: Oxytocin, eating behavior, and metabolism in humans -- Oxytocin Neurophysiology-Relation to Energy Homeostasis -- Endogenous Oxytocin Levels, Eating Behavior, and Metabolic Status in Humans -- Measurement of oxytocin -- Endogenous oxytocin levels in healthy individuals and patients with disrupted oxytocin pathways -- Oxytocin levels in obesity and metabolic disorders -- The Effects of Oxytocin Administration on Caloric Intake and Metabolism
The Effects of Oxytocin Administration in Individuals with Obesity and Suspected Insult to Oxytocin Pathways -- Therapeutic Opportunities and Challenges -- Competing interests statement -- References -- Chapter 7: The supraoptic and paraventricular nuclei in healthy aging and neurodegeneration -- The Supraoptic and Paraventricular Nuclei in Healthy Aging -- Morphological changes in aging -- Sex differences in aging -- Vasopressin -- Oxytocin -- Corticotropin-releasing hormone -- Thyrotropin-releasing hormone -- Hormone changes in aging -- Vasopressin -- Oxytocin -- Corticotropin-releasing hormone -- Thyrotropin-releasing hormone -- Circuit changes in aging -- Hypothalamic-pituitary-adrenal axis -- Hypothalamic-pituitary-thyroid axis -- The Supraoptic and Paraventricular Nuclei in Neurodegeneration -- Alzheimer's disease -- Abnormal inclusions and aggregates -- Neuronal loss and other pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Frontotemporal dementia -- Abnormal inclusions and aggregates -- Neuronal loss and other pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Amyotrophic lateral sclerosis -- Abnormal inclusions and aggregates -- Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Progressive supranuclear palsy -- Abnormal inclusions and aggregates -- Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Parkinson's disease -- Abnormal inclusions and aggregates -- Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Dementia with Lewy bodies -- Abnormal inclusions and aggregates -- Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Multiple system atrophy -- Abnormal inclusions and aggregates
Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Huntington's disease -- Abnormal inclusions and aggregates -- Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Conclusion -- References -- Chapter 8: Perinatal stress and epigenetics -- Introduction: DNA Methylation and Cellular Identity -- DNA Methylation and Gene Function -- Epigenetic Programming of the HPA Axis by Maternal Behavior and Its Reversal by Epigenetic Regulators -- Early Life Stress-Mediated Epigenetic Reprogramming of the HPA axis: Epigenetic Changes in the Hypothalamus -- Early Life Stress/Adversity Causes Broad Epigenetic Changes Across the Genome Which Are Evolutionary Conserved -- The Effect of Early Life Stress/Adversity-related Broad Epigenetic Changes in Peripheral Tissues Outside the -- Socioeconomic Positioning and Epigenetic Programming -- Early Life Stress and PTSD -- Cross-Generational Effects of Trauma -- Early Life Stress Methylation and Metabolic Control -- Epigenetic Processes Mediating Effects of Stress During Adulthood -- DNA Methylation Programming of the HPA axis in Response to ELS: A Genomic Mechanism of Adaptation -- Dynamic Epigenetic Programming in Response to Early Life Experience: Setting up Future Gene Expression Trajectories -- What Are the Mechanisms that Mediate Between Experience and DNA Methylation Alterations in the HPA axis and Somatic Tissues an -- Summary and Perspective -- Acknowledgment -- References -- Chapter 9: The hypothalamus in anxiety disorders -- Introduction -- Oxytocin -- Corticotropin-Releasing Hormone -- Thyrotropin-Releasing Hormone -- Conclusion -- Acknowledgment -- References -- Chapter 10: Congenital isolated central hypothyroidism: Novel mutations and their functional implications -- Introduction
Notes Contains table of contents for related volumes in series : Volume 179: The human hypothalamus. Anterior region -- Volume 181: The human hypothalamus. Neuroendocrine disorders -- Volume 182: The human hypothalamus. Neuropsychiatric disorders
Bibliography Includes bibliographical references and index
Subject Hypothalamus.
Infundibulum (Brain)
Human beings.
Hypothalamus
Hypothalamus, Middle
Hypothalamus, Posterior
Humans
Homo sapiens (species)
Infundibulum (Brain)
Hypothalamus.
Form Electronic book
Author Swaab, D. F. (Dick Frans), editor.
Kreier, Felix editor
Lucassen, Paul J. editor
Salehi, Ahmad editor
Buijs, Ruud M. editor
LC no. 2022508132
ISBN 9780128201077
012820107X
0128201088
9780128201084