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Title Modern management of acoustic neuroma / volume editors, Jean Régis, Pierre-Hugues Roche
Published Basel ; New York : Karger, ©2008


Description 1 online resource (xv, 261 pages) : illustrations (some color)
Series Progress in neurological surgery ; v. 21
Progress in neurological surgery ; v. 21
Contents Cover -- Contents -- In Memoriam Prof. Robert Sedan -- Editors/Editorial Assistant -- Series Editor�s Note -- Foreword -- History of Radiosurgery in Brief -- The Goals of Radiosurgery -- Accomplishments of Stereotactic Radiosurgery -- Further Efforts and Issues -- Introduction -- References -- History of Vestibular Schwannoma Surgery -- Abstract -- The Neurosurgical Period -- Harvey Cushing (1869�1939) -- Walter Dandy (1886�1945) -- Herbert Olivecrona (1891�1980) -- W.J. Atkinson -- The 1950s -- The Otoneurosurgical Period -- The 1960s
William HouseThe 1970s -- Preservation of Hearing -- The 1980s -- The 1990s Onwards -- References -- Genesis and Biology of Vestibular Schwannomas -- Abstract -- Mechanisms of Genesis and Growth -- Genetic and Epigenetic Factors: The Key Role of the Neurofibromatosis Type 2 Gene Product -- Mutation of the Neurofibromatosis Type 2 Gene, a Tumor Suppressor Gene -- Epigenetic Factors Leading to Alteration of the Neurofibromatosis Type 2 Gene Transcription -- Alternative Mechanisms of Action of Schwannomin/Merlin -- Regulation of Schwannomin/Merlin Activity
Vestibular Schwannomas and Neurofibromatosis Type 2 Gene-Unrelated ActorsHormonal Factors -- Growth Factors -- Modification of Expression of the Non-Neurofibromatosis Type 2 Gene -- Apopotic Modulation -- Conclusion -- References -- Radiobiology, Principle and Technique of Radiosurgery -- Abstract -- Radiosurgical Techniques -- Gamma Knife Radiosurgery -- Rotating Gamma System -- Charged-Particle Radiosurgery -- LINAC Radiosurgery -- Tomotherapy -- Image-Guided Radiotherapy -- Radiosurgery Technique for Vestibular Schwannomas
Pre-Radiosurgery EvaluationRadiosurgery Technique -- Radiosurgical Dose Planning -- Dose Prescription -- Dose Delivery -- Postoperative Care -- Postradiosurgery Evaluations -- Radiobiology -- The Linear-Quadratic Formula -- Radiosurgical Data and the Linear-Quadratic Formula -- Optic Nerve Tolerance Doses in Radiosurgery -- Dose-Response Analysis for Cranial Neuropathies after Acoustic Neuroma Radiosurgery -- Comparison of Postradiosurgery Injury Reactions for AVM and Meningioma -- Radiosurgery of Brain Metastases -- Conclusions -- References
Cerebellopontine Cistern: Microanatomy Applied to Vestibular SchwannomasAbstract -- The Different Methods Used to Study the Cisterns of the Brain in the Literature -- The Cerebellopontine Cistern and Its Contents -- The Trigeminal Nerve -- The Cochleovestibulofacial Bundle -- Facial Nerve (VII) -- Vestibulocochlear Nerve (VIII) -- Glossopharyngeal, Vagus and Willis� Accessory Nerves -- Vascularization -- The Acousticofacial Cistern -- Contents -- The Facial and Intermedius Nerves -- The Cochleovestibular Nerve -- Vascularization
Summary Acoustic neuroma outcomes have been greatly improved by advances in microsurgical techniques, and recently by the long-term application of radiosurgery, which has proven to be an appropriate, verifiable, and extremely clinically relevant treatment strategy. This volume brings together the latest opinions of outstanding physicians and surgeons who treat patients with acoustic neuromas, commonly known as vestibular neuromas. Since the days of Cushing, when partial tumor removal seemed the best method for saving a patient's life, the management of this relatively rare tumor has sparked enormous clinical interest. The book outlines the various stages in the evolution of vestibular schwannoma surgery and presents the full spectrum of current therapeutic possibilities. The novel concept of combining microsurgical with radiosurgical skills should eliminate problems such as facial palsy and hearing loss which were previously associated with the therapeutic management of these tumors
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject Acoustic neuroma -- Surgery
Nervous system -- Surgery.
Neuroma, Acoustic -- surgery
Neurosurgical Procedures
Nervous system -- Surgery
Neurinome de l'acoustique -- chirurgie.
Interventions neurochirurgicales.
Neurinome de l'acoustique -- Chirurgie.
Akustikustumor -- Neurochirurgie -- Aufsatzsammlung.
Neurochirurgie -- Akustikustumor -- Aufsatzsammlung.
Akustikustumor -- Radiofrequenzchirurgie -- Aufsatzsammlung.
Radiofrequenzchirurgie -- Akustikustumor -- Aufsatzsammlung.
Form Electronic book
Author Régis, Jean
Roche, Pierre-Hugues
S. Karger (Firm)
ISBN 9783805583718