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Book Cover
E-book

Title G-protein coupled receptors : methods express / edited by David Poyner and Mark Wheatley
Published Chichester, West Sussex, UK ; Hoboken, NJ : John Wiley & Sons, 2010

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Description 1 online resource (xiv, 296 pages) : illustrations
Contents G Protein-Coupled Receptors; Contents; Preface; Contributors; 1 Measurement of Ligand-G Protein-coupled Receptor Interactions; 2 Second Messenger Assays for G Protein-coupled Receptors: cAMP, Ca2+, Inositol Phosphates, ERK1/2; 3 Use of the [35S]GTP?S Binding Assay to Determine Ligand Efficacy at G Protein-coupled Receptors; 4 Quantitative Imaging of Receptor Trafficking; 5 Production of Recombinant G Protein-coupled Receptor in Yeast for Structural and Functional Analysis; 6 Monitoring GPCR-Protein Complexes Using Bioluminescence Resonance Energy Transfer
Summary G-Protein Coupled Receptors (GPCRs) are not only the largest protein family in the human genome but are also the single biggest target for therapeutic agents. Research into GPCRs is therefore growing at a fast pace and the range of techniques that can be applied to GPCRs is vast and continues to grow. This book provides an invaluable bench-side guide into the best and most up-to-date techniques for current and future research on GPCRs. With contributions from leading international authorities, this book equips readers with clear and detailed protocols for both well-known and up-and-coming tech
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Cell receptors.
Ion channels.
Receptors, Cell Surface
Ion Channels
MEDICAL -- Biochemistry.
Cell receptors
Ion channels
Form Electronic book
Author Poyner, David.
Wheatley, Mark, Dr.
LC no. 2009031411
ISBN 9780470749227
0470749229
9780470749142
0470749148