| Description |
1 online resource (xvi, 347 pages, 16 unnumbered pages of plates) : illustrations (some color) |
| Contents |
Drug discoveries by gene family / Karen E. Lackey -- G-protein coupled receptors / Stephen L. Garland and Tom D. Heightman -- Ion channels gene family : strategies for discovering ion channel drugs / Maria L. Garcia and Gregory J. Kaczorowski -- Integrins / David D. Miller -- Strategies for discovering kinase drugs / Jerry L. Adams [and others] -- Protease-directed drug discovery / Richard Sedrani, Ulrich Hommel, and Jor̈g Eder -- Small-molecule inhibitors of protein-protein interactions : challenges and prospects / Adrian Whitty -- Transporters / Anne Hersey, Frank E. Blaney, and Sandeep Modi -- Nuclear receptor drug discovery / Hiroyuki Kagechika and Aya Tanatani -- Summary and comparison of molecules designed to modulate druggable targets in the major gene families / Karen E. Lackey |
| Summary |
As research progresses and information continues to proliferate in the field of molecular design for therapeutic use, there is a need for a reference that brings current theory and proven practice together in a how-to volume. This reference guides scientists new to the field on how to design small molecules that interact with critical protein targets. The chapters condense useful material into a manageable format which is carefully organized and presented. It offers an essential resource for a variety of chemists in academia, and the biotech and pharmaceutical industries, as well as profession |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| Subject |
Pharmacogenomics.
|
|
Drugs -- Design.
|
|
Genes.
|
|
Drug Design
|
|
Genes
|
|
Ion Channels -- genetics
|
|
Models, Molecular
|
|
Pharmacogenetics -- methods
|
|
MEDICAL -- Pharmacology.
|
|
Genes
|
|
Drugs -- Design
|
|
Pharmacogenomics
|
| Form |
Electronic book
|
| Author |
Lackey, Karen
|
| ISBN |
9780470423929 |
|
0470423927 |
|
9780470423936 |
|
0470423935 |
|
1282685864 |
|
9781282685864 |
|
9786612685866 |
|
6612685867 |
|
