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Leukemias, Acute Myeloblastic -- See Leukemia, Myeloid, Acute


Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES 		  1
 

Leukemias, Acute Myelocytic -- See Leukemia, Myeloid, Acute


Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES 		  1
 

Leukemias, Acute Myelogenous -- See Leukemia, Myeloid, Acute


Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES 		  1
 

Leukemias, Acute Myeloid -- See Leukemia, Myeloid, Acute


Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES 		  1
 

Leukemias, Acute Nonlymphoblastic -- See Leukemia, Myeloid, Acute


Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES 		  1
 

Leukemias, Acute Nonlymphocytic -- See Leukemia, Myeloid, Acute


Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES 		  1
 

Leukemias, Chronic B-Cell -- See Leukemia, Lymphocytic, Chronic, B-Cell


A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease 		  1
 

Leukemias, Chronic B-Lymphocytic -- See Leukemia, Lymphocytic, Chronic, B-Cell


A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease 		  1
 

Leukemias, Chronic Granulocytic -- See Leukemia, Myelogenous, Chronic, BCR-ABL Positive


Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS 		  1
 

Leukemias, Chronic Lymphoblastic -- See Leukemia, Lymphocytic, Chronic, B-Cell


A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease 		  1
 

Leukemias, Chronic Monocytic -- See Leukemia, Myeloid


Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites 		  1
 

Leukemias, Chronic Myelocytic -- See Leukemia, Myelogenous, Chronic, BCR-ABL Positive


Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS 		  1
 

Leukemias, Chronic Myelogenous -- See Leukemia, Myelogenous, Chronic, BCR-ABL Positive


Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS 		  1
 

Leukemias, Chronic Myeloid -- See Leukemia, Myelogenous, Chronic, BCR-ABL Positive


Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS 		  1
 

Leukemias, Granulocytic -- See Leukemia, Myeloid


Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites 		  1
 

Leukemias, L3 Lymphocytic -- See Burkitt Lymphoma


A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative 		  1
 

Leukemias, Lymphocytic -- See Leukemia, Lymphoid


Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts 		  1
 

Leukemias, Lymphoid -- See Leukemia, Lymphoid


Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts 		  1
 

Leukemias, Myelocytic -- See Leukemia, Myeloid


Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites 		  1
 

Leukemias, Myelogenous -- See Leukemia, Myeloid


Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites 		  1
 

Leukemias, Myeloid -- See Leukemia, Myeloid


Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites 		  1
 

Leukemias, Ph1-Positive Myelogenous -- See Leukemia, Myelogenous, Chronic, BCR-ABL Positive


Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS 		  1
 

Leukemias, Ph1-Positive Myeloid -- See Leukemia, Myelogenous, Chronic, BCR-ABL Positive


Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS 		  1
 

Leukemias, Philadelphia-Positive Myeloid -- See Leukemia, Myelogenous, Chronic, BCR-ABL Positive


Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS 		  1
 

Leukemogenesis -- See Leukemia Etiology


  1
 

Leukemogenic Virus -- See Retroviridae


Family of RNA viruses that infects birds and mammals and encodes the enzyme reverse transcriptase. The family contains seven genera: DELTARETROVIRUS; LENTIVIRUS; RETROVIRUSES TYPE B, MAMMALIAN; ALPHARETROVIRUS; GAMMARETROVIRUS; RETROVIRUSES TYPE D; and SPUMAVIRUS. A key feature of retrovirus biology is the synthesis of a DNA copy of the genome which is integrated into cellular DNA. After integration it is sometimes not expressed but maintained in a latent state (PROVIRUSES) 		  1
  Leukemogenic Viruses -- 2 Related Subjects   2
 

Leukocytaphereses -- See Leukapheresis


The preparation of leukocyte concentrates with the return of red cells and leukocyte-poor plasma to the donor 		  1
 

Leukocytapheresis -- See Leukapheresis


The preparation of leukocyte concentrates with the return of red cells and leukocyte-poor plasma to the donor 		  1
 

Leukocyte -- See Leukocytes


White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES) 		  1
 

Leukocyte Adhesion Molecules -- See Cell Adhesion Molecules


Surface ligands, usually glycoproteins, that mediate cell-to-cell adhesion. Their functions include the assembly and interconnection of various vertebrate systems, as well as maintenance of tissue integration, wound healing, morphogenic movements, cellular migrations, and metastasis 		  1
 

Leukocyte Antigens -- See HLA Antigens


Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases 		  1
 

Leukocyte Antigens, Human -- See HLA Antigens


Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases 		  1
 

Leukocyte Chemotaxis -- See Chemotaxis, Leukocyte


The movement of leukocytes in response to a chemical concentration gradient or to products formed in an immunologic reaction 		  1
  Leukocyte Differentiation Antigens, Human -- 2 Related Subjects   2
Leukocyte Disorders -- chemically induced : Twenty years of G-CSF : clinical and nonclinical discoveries / Graham Molineux, MaryAnn Foote, Tara Arvedson, editors  2012 1
 

Leukocyte Interferon -- See Interferon-alpha


One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways 		  1
 

Leukocyte, Mononuclear -- See Leukocytes, Mononuclear


Mature LYMPHOCYTES and MONOCYTES transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules 		  1
 

Leukocyte, Polymorphonuclear -- See Neutrophils


Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes 		  1
Leukocyten.   2
  Leukocytes -- 2 Related Subjects   2
Leukocytes   13
Leukocytes -- immunology   3
Leukocytes, Mononuclear   4
Leukocytes -- physiology   3
 

Leukocytes, Polymorphonuclear -- See Neutrophils


Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes 		  1
 

Leukocytophereses -- See Leukapheresis


The preparation of leukocyte concentrates with the return of red cells and leukocyte-poor plasma to the donor 		  1
 

Leukocytopheresis -- See Leukapheresis


The preparation of leukocyte concentrates with the return of red cells and leukocyte-poor plasma to the donor 		  1
 

Leukoderma -- See Vitiligo


  1
  Leukodystrophy -- 2 Related Subjects   2
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