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E-book

Title Current topics in innate immunity II / John D. Lambris, George Hajishengallis, editors
Published New York, NY : Springer, [2012]

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Description 1 online resource (1 volume) : illustrations
Series Advances in experimental medicine and biology, 0065-2598 ; 946
Advances in experimental medicine and biology ; v. 946.
Contents 880-01 Pentraxins in humoral innate immunity -- galectins as pattern recognition receptors: structure, function, and evolution -- the role of innate immunity in trafficking of hematopoietic stem cells -- an emerging link between activation of complement cascade and chemotactic gradients of bioactive sphingolipids -- interaction of the microbiome with the innate immune response in chronic wounds -- keystone species and community service through manipulation of innate immunity -- a conserved host and pathogen site on immunoglobulins: structural and functional aspects -- advances in understanding the structure, function, and mechanism of the scin and efb families of staphylococcal immune evasion proteins -- granzyme b: a new crossroad of complement and apoptosis -- role of c3, c5 and anaphylatoxin receptors in acute lung injury and in sepsis -- complement mediated ocular angiogenesis -- platelets, complement, and contact activation: partners in inflammation and thrombosis -- nuclear factor-[kappa]b in immunity and inflammation: the treg and th17 connection -- function of act1 in il-17 family signaling and autoimmunity -- differential effect of inhibiting md-2 and cd14 on lps- versus whole e. coli bacteria-induced cytokine responses in human blood -- zebrafish: model for the study of inflammation and the innate immune response to infectious diseases -- monocyte-derived inflammatory dendritic cells in the granuloma during mycobacterial infection -- nk/dc crosstalk in anti-viral response -- innate-adaptive crosstalk: how dendritic cells shape immune responses in the cns -- nutritional immunity: homology modeling of nramp metal import
880-01/(S Preface; Contents; List of Contributors; Pentraxins in Humoral Innate Immunity; 1 Introduction; 2 The Pentraxin Superfamily; 3 The Short Pentraxins in Innate Immunity; 4 The Long Pentraxin PTX3; 4.1 Gene Organization and Expression; 4.2 Protein Structure; 4.3 Interaction with Complement and Fcγ Receptors; 4.4 PTX3 in Pathogen Recognition and Inflammation; 4.5 Self versus Modified Self-Discrimination; 4.6 PTX3 Role in Tissue Remodelling; 4.7 Diagnostic and Prognostic Potential of PTX3 in Infectious Disorders; 5 Concluding Remarks; References
Summary Annotation Mounting evidence in the past decade indicates that innate immunity mediates functions above and beyond first-line defense against infection. It is now appreciated that innate immune mechanisms are critically involved in the development of adaptive immunity and, moreover, the regulation of diverse physiological and homeostatic processes. The latter explains why deregulation of innate immunity may lead to pathological disorders that are not necessarily or directly related to host defense. This Volume compiles the latest advances in this rapidly evolving field as presented by eminent scientists at the 7th International Aegean Conference on Innate Immunity in Rhodes, Greece. It includes topics related to the biology and function of Toll-like and other pattern-recognition receptors, complement and its crosstalk with other physiological systems, inflammatory mechanisms and diseases, natural killer cells, and the cooperative interplay between innate and adaptive immune cells. This book is an excellent source of information for researchers and clinicians with interests in immunology, host-microbe interactions, and infectious and inflammatory diseases
Analysis Medicine
Immunology
Toxicology
Medical virology
Microbiology
Biomedicine
Infectious Diseases
Pharmacology/Toxicology
farmacologie
pharmacology
toxicologie
biomedische wetenschappen
microbiologie
virologie
virology
infectieziekten
immunologie
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references
Notes English
Subject Natural immunity.
Lymphocytes.
Immunity.
Cell receptors.
Immune system.
Membrane proteins.
Leucocytes.
Proteins.
Blood cells.
Blood.
Cells.
Anatomy.
Killer cells.
Biological Phenomena
Receptors, Immunologic
Lymphocytes
Microbiological Phenomena
Immunity
Leukocytes, Mononuclear
Receptors, Cell Surface
Immune System Phenomena
Membrane Proteins
Phenomena and Processes
Leukocytes
Proteins
Immune System
Blood Cells
Amino Acids, Peptides, and Proteins
Blood
Hemic and Immune Systems
Cells
Anatomy
Chemicals and Drugs
Killer Cells, Natural
Adaptive Immunity
Receptors, Pattern Recognition
Immunity, Innate
Host-Pathogen Interactions
protein.
blood (animal material)
anatomy.
Proteins
Membrane proteins
Lymphocytes
Leucocytes
Killer cells
Immunity
Immune system
Cells
Cell receptors
Blood cells
Blood
Anatomy
Natural immunity
Form Electronic book
Author Lambris, J. D. (John D.)
Hajishengallis, George
ISBN 9781461401063
1461401062
1461401054
9781461401056
1283351838
9781283351836