| Description |
1 online resource (xvii, 235 pages) |
| Series |
Birkhäuser advances in infectious diseases |
|
Birkhäuser advances in infectious diseases.
|
| Contents |
Regulation of Adaptive Immunity in the Elderly -- Does Innate Immunity Get Old? -- Thy( -im)munosenescence: The Ageing of the Thymus and Its Impact on the Immune System -- Characteristics of B Cells and B Cell Responses in Aged Individuals -- Mechanisms of Immune Protection to Pneumococcal Infection in the Young and the Elderly -- CMV Subversion of the Immune System in Later Life -- Aging and Autoimmunity -- Vaccination in the Elderly -- Immunosenescence and the 3Rs: Restoration, Replacement and Reprogramming -- Immunosenescence and Its Correction -- Novel Strategies for Improved Vaccines for the Elderly: The Example of Influenza |
| Summary |
Annotation As individuals age, their ability to respond to andclear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and general immune dysfunctions. Most remarkably, the efficacy of vaccines is frequently decreased in elderly persons. Therefore, age-associated dysfunctions of the humoral and cellular immune responses have a strong clinical impact. Improving our understanding of the aged immune system is crucial in developing effective prevention and treatment programs that will facilitate healthy aging and improve the quality of life of the elderly population. The aim of this volume is to summarize current knowledge on the cellular and molecular aspects of the aging immune system, with an emphasis on infectious diseases and new therapeutic approaches |
| Analysis |
Medicine |
|
Immunology |
|
Biomedicine |
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Molecular Medicine |
|
biomedische wetenschappen |
|
geneeskunde |
|
immunologie |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Notes |
Includes index |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Immune system -- Aging
|
|
Age factors in disease.
|
|
Aging -- immunology
|
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Immunity -- physiology
|
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Age Factors
|
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Disease Susceptibility -- immunology
|
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Longevity -- immunology
|
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MEDICAL -- Immunology.
|
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Immunology
|
|
Medicine
|
| Form |
Electronic book
|
| Author |
Thiel, Andreas, 1964 December 11-
|
| ISBN |
9783034602198 |
|
3034602197 |
|
1283911574 |
|
9781283911573 |
|
3034602189 |
|
9783034602181 |
|
