Limit search to available items
Book Cover
E-book
Author Dhas, Namdev

Title Advanced Targeting of the Lymphatic System
Published Cham : Springer, 2024

Copies

Description 1 online resource (0 p.)
Contents Intro -- Foreword -- Preface -- Contents -- Contributors -- About the Editors -- Chapter 1: Lymphatic System: History, Anatomy, Physiology, Challenges, and Opportunities -- 1 Introduction -- 2 History -- 2.1 Historical Origin -- 2.2 Renaissance Findings -- 2.3 Developments in the Seventeenth and Eighteenth Centuries -- 2.4 The Modern Age -- 2.5 Contemporary Studies -- 3 Anatomy -- 3.1 Lymphatic Capillaries -- 3.2 Lymphatic Vessels -- 3.3 Lymphatic Ducts -- 3.4 Lymphatic System Valves -- 3.5 Lymph Nodes -- 3.6 Lymphoid or Lymphatic Organs -- 4 Physiology -- 4.1 Lymph Flow
4.1.1 Formation of Lymph -- 4.1.2 Lymph Propulsion -- 4.2 Physiological Function -- 5 Challenges and Opportunities of Lymphatic System -- 5.1 Challenges -- 5.2 Opportunities -- 5.2.1 Lymphatic Imaging -- 5.2.2 Opportunities in Research -- 5.2.3 Opportunities in Clinical Frontiers -- 5.2.4 Mathematical Modeling and System Engineering -- 5.2.5 Engineering Solutions for Lymphedema -- 6 Conclusion -- References -- Chapter 2: Advancements in Brain Lymphatic System and Its Involvement in Neurological Diseases -- 1 Introduction -- 1.1 Alzheimer's Disease -- 1.2 Multiple Sclerosis -- 1.3 Parkinsonism
1.4 Other Diseases -- 2 G-Lymphatic Pathway: The Garbage Truck of the Brain -- 2.1 Vital Components of the Brain Lymphatic System -- 2.1.1 Perivascular Drainage Pathways -- 2.1.2 Glymphatic System -- 2.1.3 The Relationship Between CSF Circulation and the Olfactory/Cervical Lymphatic Drainage Route and Meningeal Lymphatic Vessels -- 2.1.4 Connection Between the Components of the Brain Lymphatic Drainage System -- 2.2 Physiological Function of the Brain Lymphatic System -- 2.2.1 Aging -- 2.2.2 Genetic Factors -- 2.2.3 Sleep -- 2.2.4 Body Posture
2.2.5 Aquaporin-4 (AQP4) Expression and Localization -- 2.2.6 Disease Conditions -- 3 Impairments and Dysfunctions in Brain Lymphatic System -- 4 Targeting the Lymphatic System in Neurological Disorders -- 4.1 Neurodegenerative Diseases -- 4.2 Neurovascular Diseases -- 4.3 Neuroinflammatory Diseases -- 4.4 Brain Injury -- 4.5 Brain Tumor -- 4.6 HIV-Associated Neurocognitive Disorder (HAND) -- 5 Conclusion and Outlook -- References -- Chapter 3: Lymphatic System in the Eye -- 1 Introduction -- 1.1 Presence of Lymphatics in the Eye -- 1.2 Distribution of Lymphatics Around the Eye
1.2.1 Conjunctival Lymphatics -- 1.2.2 Corneolimbus Lymphatics -- 1.2.3 Ciliary Body -- 1.3 Ocular Homeostasis Through Fluid Transport -- 1.4 Molecular Mechanisms for Lymphatic Development in Eye -- 1.5 General In Vivo Fate of Drug After Ocular Administration: Role of Lymphatics -- 2 Scope of Drug Targeting and Therapeutic Applications in Ocular Lymphatics -- 2.1 Applications in Corneal Transplants to Avoid Graft Rejection -- 2.2 Ocular Inflammatory Conditions -- 2.2.1 Dry Eye Disease (DED) -- 2.3 Tumors in Ocular Area -- 2.3.1 Melanoma of Ciliary Body -- 2.3.2 Carcinoma of Conjunctiva
Summary This book goes in depth about the lymphatic system and the functions of the lymphatic organs, lymphatic tissues, and lymphatic vessels. The book addresses various types of diseases in which the lymphatic system can act as a targeting site for drug absorption and suggests strategies to treat these different infections of the lymphatic system. This book is intended for academicians who work in fields related to the lymphatic system, novel drug delivery systems, pharmaceutical science, novel-material sciences, as well as professionals in the medical, nursing, or other health care industries
Notes Description based upon print version of record
2.3.3 Melanoma of Conjunctiva
Subject Lymphatics.
Toxicology.
Lymphatic System
Drug Delivery Systems
Toxicology
toxicology.
Form Electronic book
Author Patel, Jayvadan K
Pathak, Yashwant V
ISBN 9783031648281
3031648285