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Title Cellular therapy of cancer : development of gene therapy based approaches / editor, Robert E. Hawkins
Published Hackensack, NJ : World Scientific, ©2014


Description 1 online resource
Contents Ch. 1. Challenges of T-cell therapy / Naomi Taylor, Anna Mondino and Balbino Alarcon -- ch. 2. Gene transfer into T cells / David Gilham and Hinrich Abken -- ch. 3. TCR-engineered T cells / Reno Debets and Ton Schumacher -- ch. 4. T-bodies: Antibody-based engineered T-cell receptors / John Bridgeman [and others] -- ch. 5. T-cell engineering and expansion -- GMP issues / Cor Lamers and Ryan Guest -- ch. 6. Clinical trial design / Robert Hawkins, John Haanen and Fiona Thistlethwaite
Summary Cancer research has progressed enormously in recent years. This review volume will address recent findings in the area of T-cell therapy for cancer, including use of tumour infiltrating lymphocytes (TILs) as a therapy for melanoma, choice of target antigens, advances in engineered receptors, methods of gene transfer to T cells, review of cell processing methods and clinical trial design. Written by leadings scientists in the field, this up-to-date review on cancer research will be an important reference source to the researchers and healthcare professionals in the field
Bibliography Includes bibliographical references
Notes Print version record
Subject Cancer -- Treatment.
T cells -- Research
Cellular therapy -- Research
Lymphocytes, Tumor-Infiltrating
Neoplasms -- therapy
Genetic Therapy -- methods
Immunotherapy, Adoptive -- methods
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Cancer -- Treatment
T cells -- Research
Form Electronic book
Author Hawkins, Robert E., editor
ISBN 9789814295147