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Book Cover
E-book
Author Burgess, Stephen, author

Title Mendelian randomization : methods for using genetic variants in causal estimation / Stephen Burgess, Simon G. Thompson
Published Boca Raton, FL : Chapman & Hall/CRC, [2015]
©2015

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Description 1 online resource (xiv, 210 pages) : illustrations
Series Chap & Hall/CRC interdisciplinary statics series
Chap & Hall/CRC interdisciplinary statics series
Contents Introduction and motivation -- What is Mendelian randomization? -- Assumptions for causal inference -- Methods for instrumental variable analysis -- Examples of Mendelian randomization analysis -- Generalizability of estimates from Mendelian randomization -- Weak instruments and finite-sample bias -- Multiple instruments and power -- Multiple studies and evidence synthesis -- Example : the CRP CHD genetics collaboration -- Future directions
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Medical genetics -- Statistical methods
Human genetics -- Variation.
Mendelian Randomization Analysis -- methods
Genetic Variation
Statistics as Topic -- methods
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Human genetics -- Variation
Medical genetics -- Statistical methods
Form Electronic book
Author Thompson, Simon G., author
ISBN 9781466573185
146657318X