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E-book
Author Staff, Institute of Medicine

Title Modern Methods of Clinical Investigation
Published Washington : National Academies Press, 1900

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Description 1 online resource (244 pages)
Contents ""Modern Methods of Clinical Investigation""; ""Copyright""; ""Acknowledgments""; ""Preface""; ""Contents""; ""List of Abbreviations""; ""1 Medical Technology Development: An Introduction to the Innovation-Evaluation Nexus ""; ""PUTTING CLINICAL EVALUATION IN CONTEXT""; ""ISSUES IN INNOVATION AND EVALUATION: THE CASE OF STABLE ANGINA PECTORIS""; ""Beta-Blockers""; ""Coronary Artery Bypass Grafting""; ""PTCA Catheter Equipment""; ""Evaluative Shortcomings in Technology Development""; ""IMPROVING THE INNOVATION-EVALUATION NEXUS""; ""The Selection of Endpoints in Evaluative Research""
""The Selection of Methods for Clinical Investigation""""Policy Mechanisms for Improving Developmental Decision Making""; ""REFERENCES""; ""2 The Selection of Endpoints in Evaluative Research ""; ""SURROGATE VERSUS CLINICAL ENDPOINTS""; ""CLINICAL ENDPOINTS""; ""SURROGATE ENDPOINTS""; ""REFERENCES""; ""3 Advances in Health Status Measurement: The Potential to Improve Experimental and Non-Experimental Data Collection""; ""THE CONDUCT OF CLINICAL TRIALS""; ""MEASUREMENT OF QUALITY OF LIFE AND OF HEALTH STATUS""; ""INCLUSION OF QUALITY OF LIFE AND HEALTH STATUS MEASURES IN CLINICAL TRIALS""
""FOUR PROBLEMS REGARDING THE MEASUREMENT OF HEALTH STATUS IN CLINICAL TRIALS""""REFERENCES""; ""4 What Is Outcomes Research? ""; ""WHICH RATE IS RIGHT?""; ""ENGAGING PATIENTS IN THE DECISION PROCESS""; ""EXTENDING ASSESSMENT TO ALL RELEVANT TREATMENT THEORIES""; ""THE EVALUATIVE CLINICAL SCIENCES AND THE FUTURE OF MEDICINE""; ""REFERENCES""; ""5 Strengths and Weaknesses of Health Insurance Data Systems for Assessing Outcomes""; ""STRENGTHS""; ""System-Wide, Population-Based Data""; ""Efficacy versus Effectiveness""; ""Large Numbers and Time Series""; ""Events Unaffected by Recall""
""Unobtrusive Nature""""Multiple Comparisons""; ""Design Flexibility""; ""Potential for Multiple Projects""; ""Focus on Risks""; ""Clinical Decision Making""; ""WEAKNESSES""; ""Structural Limitations""; ""Bias Due to Reporting and Coding""; ""Bias Due to Differential Contact""; ""Benefits of Treatment""; ""CONTROVERSIAL AREAS""; ""Risk Adjustment""; ""Outcome Measures""; ""EXPANDING DATA BASES""; ""Record Linkage""; ""Primary Data Collection""; ""DISCUSSION""; ""REFERENCES""; ""6 Prescription-Event Monitoring: An Example of Total Population Post-Marketing Drug Surveillance ""
""""THE NUMBERS GAME""""""VOLUNTARY REPORTING SYSTEMS""; ""POST-MARKETING SURVEILLANCE""; ""PRESCRIPTION-EVENT MONITORING""; ""COMPARATIVE STUDIES OF NSAIDS""; ""POST-MARKETING SURVEILLANCE AND POST-MARKETING CLINICAL TRIALS""; ""CONCLUSION""; ""REFERENCES""; ""7 The Role of Decision Analysis in the Translation of Research Findings into Clinical Practice ""; ""DECISION ANALYSIS AT THE INTERFACE BETWEEN CLINICAL INVESTIGATION AND CLINICAL PRACTICE""; ""WHAT DECISION ANALYSIS IS""; ""THE LIMITATIONS OF DECISION ANALYSIS: WHAT IT IS NOT""
Notes ""Setting priorities and parameters for clinical investigation""
Print version record
Subject Medical technology -- Evaluation -- Congresses
Medical innovations -- Evaluation -- Congresses
Medical care -- Technological innovations -- Congresses
Meta-analysis -- Congresses
Medical care -- Technological innovations
Medical innovations -- Evaluation
Medical technology -- Evaluation
Meta-analysis
Genre/Form Conference papers and proceedings
Form Electronic book
Author Gelijns, Annetine C
ISBN 9780309543569
0309543568