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Book Cover
E-book
Author Wang, Guanyu (Physicist)

Title Analysis of complex diseases : a mathematical perspective / Guanyu Wang
Published Boca Raton : Taylor & Francis, [2014]
©20
©2014

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Description 1 online resource (228 pages) : illustrations (some color)
Contents Food intake and energy metabolism -- Glucose homeostasis -- Optimal glucose homeostasis -- Bistability as a fundamental phenomenon -- Biomolecular network -- P13K-AKT-TOR pathway -- Diseases related to metabolism -- Mathematical modeling of the P13K-AKT-TOR Pathway -- Fundamental decomposition -- Normal phenotype -- Disease phenotypes -- Tao of diseases
Summary A complex disease involves many etiological and risk factors operating at multiple levels-molecular, cellular, organismal, and environmental. The incidence of such diseases as cancer, obesity, and diabetes are increasing in occurrence, urging us to think fundamentally and use a broader perspective to identify their connection and revolutionize treatments. The understanding of biological data derived from studying diseases can be enhanced by theories and mathematical models, which clarify the big picture and help to reveal the overarching mechanisms that govern complex biological phenomena
Bibliography Includes bibliographical references
Notes Print version record
Subject Metabolism -- Disorders.
Biological models.
Metabolic Diseases -- complications
Models, Biological
Metabolic Diseases
Phosphatidylinositol 3-Kinases -- metabolism
Systems Biology -- methods
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Biological models
Metabolism -- Disorders
Form Electronic book
ISBN 9781466572232
146657223X
1466572213
9781466572218