| Description |
1 online resource (xvii, 431 pages, 8 unnumbered pages of plates) : illustrations (some color) |
| Contents |
Micro mining : computational approaches to miRNA discovery / Adam Grundhoff -- Animal microRNA gene prediction / Ola Snv?e and Pål St?rom -- A suite of resources for the study of miRNA ontology and function / Praveen Sethupathy, Molly Megraw, and Artemis G. Hatzigeorgiou -- Regulation of translation and mRNA stability by Hfq-binding small RNAs in Escherichia coli / Hiroji Aiba -- Mechanisms by which microRNAs regulate gene expression in animal cells / Yang Yu and Timothy W. Nilsen -- The microRNAs of C. elegans / Mona J. Nolde and Frank J. Slack -- Isolation and characterization of small RNAs in C. elegans / Chisato Ushida and Yusuke Hokii -- MicroRNA tales in fly development / Utpal Bhadra [and others] -- RNA interference and miRNAs in zebrafish / Alex S. Flynt, Elizabeth J. Thatcher, and James G. Patton -- Biogenesis and function of plant microRNAs / Zoltan Havelda -- Endogenous small RNA pathways in Arabidopsis / Manu Agarwal, Julien Curaba, and Xuemei Chen |
|
How to assay miRNA expression : a technology guide / Mirco Castoldi, Vladimir Benes, and Martina U. Muckenthaler -- Methods to quantify microRNA gene expression / Lori A. Neely -- Regulation of alternative splicing by microRNAs / Rajesh K. Gaur -- Recent progress in polymerase II-mediated intronic microRNA expression systems / Shi-Lung Lin and Shao-Yao Ying -- MicroRNA-based RNA polymerase II expression vectors for RNA interference in mammalian cells / Anne B. Vojtek [and others] -- Transgenic RNAi : a fast and low-cost approach to reverse genetics in mammals / Linghua Qiu and Zuoshang Xu -- Symphony of AIDS : an miRNA-based therapy / Yoichi R. Fujii -- MicroRNAs and cancer : connecting the dots / Sumedha D. Jayasena -- Mammalian transcriptional gene silencing by small RNAs / Daniel H. Kim and John J. Rossi -- Regulation of gene expression by RNA mediated transcriptional gene silencing / Kevin V. Morris |
| Summary |
Research demonstrates that defects in the processing mechanisms of small non-coding RNAs are linked to various human diseases. This text explores microRNAs and their functional roles in cells and organisms. It includes a study of microRNAs in development, cancer, and viruses |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Small interfering RNA.
|
|
MicroRNAs -- genetics
|
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RNA, Small Interfering
|
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Gene Expression Regulation -- genetics
|
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SCIENCE -- Life Sciences -- Molecular Biology.
|
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Small interfering RNA
|
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Genregulation
|
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Small RNA
|
| Genre/Form |
Aufsatzsammlung.
|
| Form |
Electronic book
|
| Author |
Gaur, Rajesh K., 1961-
|
|
Rossi, John J
|
| ISBN |
9781420008708 |
|
1420008706 |
|
9780429121692 |
|
0429121695 |
|
