| Description |
1 online resource |
| Contents |
A perspective on the future clinical impact of genetic diagnosis and gene-based drug therapies for patient health / Julian W. Tang -- Virally-encoded microRNA (miRNA): candidates for gene silencing / Ralph A. Tripp [and others] -- Development of gene profile-responsive antisense agents / Sergei A. Kazakov and Brian H. Johnston -- Gene profiles in drug development: applications in target identification, biomarker discovery, and compound characterization / Eric A.G. Blomme and Dimitri Semizarov -- Gene profiles and cancer / Beverly A. Teicher -- RNA viruses and RNA-based drugs: a perfect match for RNA delivery and the identification of candidate therapeutic target inflammatory molecules / Brett A. Lidbury [and others] -- Ethical considerations for a genetic future in diagnosis and drug development / Lexie Brans and Brett A. Lidbury |
| Summary |
Featuring contributions from leaders in the pharmaceutical industry, "Gene Profiles in Drug Design" explores the processes and technologies that yield gene profile based drugs. Each chapter focuses on one component or step in the process of translating abstract gene profiles into tangible new drugs. The first part of the text compares the advantages and pitfalls of various methods that have been used to generate gene profiles. The next section discusses current uses of gene profiles in drug design, including lead identification, and addresses legal issues such as FDA drug data submission. This book concludes with a look at emerging technologies that use gene profiles to design high specificity drugs |
| Notes |
"A CRC title." |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Pharmacogenetics.
|
|
Drugs -- Design.
|
|
Genetic regulation.
|
|
Drug Design
|
|
Gene Expression Profiling
|
|
Pharmacogenetics
|
|
Gene Expression Regulation
|
|
Genetic Therapy -- methods
|
|
MicroRNAs -- therapeutic use
|
|
MEDICAL -- Pharmacology.
|
|
Genetic regulation
|
|
Drugs -- Design
|
|
Pharmacogenetics
|
| Form |
Electronic book
|
| Author |
Lidbury, Brett A.
|
|
Mahalingam, Suresh.
|
| ISBN |
1420019384 |
|
9781420019384 |
|
