Description |
1 online resource : illustrations (chiefly color) |
Contents |
1. The role of natural selection in evolution / Mario A. Fares -- 2. Identifying evolution signatures in molecules / Mario A. Fares -- 3. Modeling evolution of molecular sequences / Mario A. Fares -- 4. Identifying natural selection with molecular data / Mario A. Fares -- 5. Inferring functional divergence in protein sequences / Mario A. Fares and Christina Toft -- 6. The influence of recombination on the estimation of selection from coding sequence alignments / Miguel Arenas and David Posada -- 7. Why proteins evolve at different rates : the determinants of proteins' rates of evolution / David Alvarez-Ponce -- 8. The network framework of molecular evolution / Ludovica Montanucci, Hafid Laayouni and Jaume Bertranpetit -- 9. Molecular coevolution : methods and applications / Mario A. Fares and Juan Pablo Labrador |
Summary |
"This book summarizes the knowledge in the field of methods to identify signatures of natural selection. A number of mathematical models and methods have been designed to identify the fingerprints of natural selection on genes and genomes. Such methods are provided in a simple and direct way so that students of different disciplines can navigate through molecular fitness landscapes using complex methods with a basic knowledge on bioinformatics. A collection of the main methods to detect selection in protein-coding genes and amino acid sequences is given at different levels of complexity, from nucleotides to proteins and molecular networks. The importance of identifying natural selection in genes and genomes through the methods described in this book transcends the bioinformatics and computational biology fields, presenting applications for experimental biologists in a straightforward and understandable way"--Provided by publisher |
Notes |
"A science publishers book." |
Bibliography |
Includes bibliographical references |
Notes |
Online resource; title from PDF title page (Ebsco, viewed December 17, 2014) |
Subject |
Evolutionary genetics -- Methodology
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Molecular evolution -- Methodology
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Natural selection.
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Molecular evolution.
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Selection, Genetic
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Evolution, Molecular
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SCIENCE -- Life Sciences -- Biochemistry.
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SCIENCE -- Life Sciences -- Genetics & Genomics.
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Molecular evolution
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Natural selection
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Form |
Electronic book
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ISBN |
9781482263732 |
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1482263734 |
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1482263726 |
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9781482263725 |
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9781322638089 |
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132263808X |
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