| Description |
1 online resource (219 pages) |
| Contents |
Preface; Contents; 1: Human Oral Cancer (Epidemiology and Characteristic); 1.1 Introduction; 1.2 Oral Cancer Epidemiology; 1.2.1 Incidence and Mortality; 1.2.2 Age and Gender; 1.2.3 Site; 1.2.4 Trends and Variations; 1.2.5 2035 Projection; 1.2.6 Survival; 1.3 Clinical Characteristics; 1.4 Early Detection and Prevention of Oral Cancer; 1.4.1 Primary Prevention; 1.4.2 Secondary Prevention (Screening); References; 2: Novel Developments in the Molecular Genetic Basis of Oral Squamous Cell Carcinoma (OSCC); 2.1 Introduction; 2.2 Transcriptional Factors |
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2.3 Tumor Suppressor Genes or Anti-oncogenes2.4 Proto-oncogenes and Oncogenes; 2.5 Gene Expression; 2.6 Cell Surface Receptors; 2.7 Epigenetic Changes; 2.8 Chromosomal Instability and Copy Number Variation; 2.9 mtDNA Mutation; 2.10 Telomeres and Telomerase; 2.11 Microsatellite Instability and Alteration; 2.12 Noncoding RNA; 2.13 MicroRNA (miRNA); 2.14 Long Noncoding RNAs (lncRNAs); References; 3: Oral Cancer: After the Completion of the Human Genome Project; 3.1 Gene Profiling: (A Personal Journey); 3.2 Drug Design to Shut Off Bad Genes; References; 4: Smoking and Oral Cancer |
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4.1 Introduction4.2 History of Tobacco Usage; 4.3 Cigarettes and Other Forms of Tobacco Preparations; 4.4 Composition and Carcinogenesis; 4.5 Effects on Oral Health; 4.5.1 Oral Hygiene and Aesthetics; 4.5.2 Oral Mucosal Diseases: Nonmalignant; 4.5.3 Oral Premalignant Disorders; 4.5.4 Oral Cancer; 4.6 Prevention Strategies; References; 5: Alcohol and Oral Cancer; 5.1 Introduction; 5.2 Alcohol and Oral Cancer: Epidemiological Evidence; 5.3 Alcoholic Beverages and Weekly Consumption; 5.4 Topical Effects; 5.5 Systemic Effects; 5.6 Synergistic Effects with Tobacco Use |
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5.7 Alcohol-Related Oral Carcinogenesis5.8 Alcohol-Containing Mouthwashes and Oral Cancer; 5.9 Prevention; References; 6: High-Risk Human Papillomaviruses and Epstein-Barr Virus Presence and Crosstalk in Human Oral Carcinogenesis; 6.1 Introduction; 6.2 High-Risk Human Papillomaviruses (HPVs) in Human Cancer; 6.3 Epstein-Barr Virus (EBV) in Human Cancer; 6.4 High Risk of HPVs and EBV in Human Oral Cancer; 6.5 Conclusion and Perspectives; References; 7: Oral Cancer: Epidemiology and Infections (Bacterial and Fungal) Global Incidence; 7.1 Introduction |
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7.2 Worldwide Incidence of Oral Cancer by Gender, Age and Primary Site7.3 Oral Cancer Mortality and Survival; 7.4 Bacteria and Cancer; 7.4.1 Anatomy; 7.4.2 Clinical Presentation; 7.4.3 Pathology; 7.4.4 Virus; 7.4.4.1 HPV; 7.4.4.2 Human Immunodeficiency Virus; 7.4.4.3 Herpes Simplex Virus; 7.4.5 Dental Considerations; 7.4.5.1 Hygiene; 7.4.5.2 Dentures; 7.4.5.3 Oral Cancer in the UAE; References; 8: Oral Cancer and Chewing Habits; 8.1 Introduction; 8.2 Oral Cancer Statistics: Global Incidence, Prevalence, Mortality, and Survival |
| Summary |
This book aims to provide the reader with a complete understanding of the development of oral cancer by explaining the role of a wide variety of implicated risk factors and identifying their gene targets and key regulators. Some of the discussed risk factors are well known, including smoking, alcohol, betel quid chewing, and oncoviruses such as high-risk human papillomaviruses and Epstein-Barr virus; however, careful attention is also paid to less widely recognized factors, such as Qat chewing and yerba Mate consumption. The book concludes by describing and evaluating the most important strategies currently available for the prevention of oral carcinogenesis in humans. In presenting the most up-todate research and knowledge on these topics, this book will serve as a valuable source of up-to-date information for oncologists, cancer scientists, and medical students |
| Notes |
8.3 Epidemiology in Asia: A Region with High Burden of Oral Cancer |
| Bibliography |
Includes bibliographical references at the end of each chapters |
| Notes |
Print version record |
| Subject |
Mouth -- Cancer -- Etiology
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Mouth Neoplasms -- etiology
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Mouth Neoplasms -- prevention & control
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Mouth -- Cancer -- Etiology
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| Genre/Form |
Electronic book
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| Form |
Electronic book
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| Author |
Al Moustafa, Ala-Eddin
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| ISBN |
9783319480541 |
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3319480545 |
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