Description |
xii, 250 pages, 8 unnumbered pages of color plates : illustrations ; 26 cm |
Contents |
Ageing of the human neuromuscular system : pathological aspects / W. King Engel and Valerie Askanas -- Aging of the human neuromuscular system : clinical considerations / W. King Engel and Valerie Askanas -- Aging of the human neuromuscular system : patient vignettes / W. King Engel, Shalini Mahajan, Valerie Askanas -- Mitochondrial changes in ageing with particular reference to muscle, and possible clinical consequences / Salvatore DiMauro, Eric Schon, Michio Hirano -- Protein degradation in ageing cells and mitochondria : relevance to the neuromuscular system / Jenny Ngo and Kelvin J. A. Davies -- Human muscle protein metabolism in relation to exercise and aging : potential therapeutic applications / Micah J. Drummond, Blake B. Rasmussen -- Pathogenesis of sporadic inclusion-body myositis / Valerie Askanas, W. King Engel, Anna Nogalska -- Inflammatory and autoimmune features of inclusion-body myositis / Marinos C. Dalakas -- Sporadic inclusion-body myositis: clinical symptoms, physical findings, and diagnostic investigations / Frank L. Mastaglia -- Pathologic diagnostic criteria of sporadic inclusion-body myositis and hereditary inclusion-body myopathy muscle biopsies / Valerie Askanas and W. King Engel -- Function and mutations of the GNE gene leading to distal myopathy with rimmed vacuoles hereditary inclusion-body myopathy, animal models, and potential treatments / May Christine V. Malicdan, Satoru Noguchi, Ichizo Nishino -- GNE myopathy (hereditary inclusion-body myopathy/distal myopathy with rimmed vacuoles): clinical features and epidemiology / Zohar Argov, Ishizo Nishino, Ikiyo Nonaka -- Consequences of the hereditary inclusion-body myopathy-characteristic GNE mutations on muscle proteins in vivo and in vitro / Aldobrando Broccolini and Massimiliano Mirabella -- Function and structure of VCP mutations leading to inclusion-body myopathy associated with Paget disease of bone and frontotemporal dementia / Cezary Wojcik -- Clinical spectrum of VCP myopathy, Paget disease, and frontotemporal dementia : experimental models and potential treatments / Virginia Kimonis ...[et al] -- Drosophila and mouse models of hereditary myopathy caused by mutations in VCP / Nisha M. Badders and J. Paul Taylor |
Notes |
Formerly CIP. Uk |
Bibliography |
Includes bibliographical references and index |
Subject |
Muscles -- Aging.
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Myositis.
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Myositis, Inclusion Body -- physiopathology.
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Aging.
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Author |
Askanas, Valerie.
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Engel, W. King.
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LC no. |
2011029718 |
ISBN |
1405196467 |
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9781405196468 (hardcover : alk. paper) |
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