| Description |
1 online resource : illustrations |
| Contents |
Foreword; Preface; References; Acknowledgments; Contents; Contributors; Chapter 1: Introduction; Breast Cancer Incidence and Mortality; Prevalence of Breast Cancer Survivors; Population Characteristics of Breast Cancer Survivors; Tumor Characteristics; Breast Cancer Stage; Breast Cancer Biology; Treatment Overview for Early Breast Cancer; Surgery; Adjuvant Chemotherapy; Adjuvant Trastuzumab (Herceptin®); Adjuvant Radiotherapy; Adjuvant Endocrine Therapy; Summary; References; Part I: Disease Recurrence; Chapter 2: Predicting Risk of Disease Recurrence; Introduction |
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What Does Recurrence Mean? What Are the Risks of Recurrence?; Why Do We Need to Better Identify the Risk of Recurrence?; How Can We Identify Those at Highest Risk?; Intrinsic Subtypes; Prognostic Versus Predictive Tests; Non-molecular Decision Aids; Nottingham Prognostic Index; Adjuvant! Online; Predict; The IHC4 + C Score; Commercially Available Molecular Assays; Recurrence Score; Prosigna® ROR; Endopredict®; Mammaprint; Breast Cancer Index; Other Biomarkers for Predicting Risk of Recurrence; What Are the Timeframes for Relapse?; What Are the Patterns of Relapse? |
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ConclusionReferences; Chapter 3: Detection of Recurrence: Clinical Follow-Up; Guidelines; Clinical Examination and Routine Appointments; Identification of Early Secondary Disease; Models of Follow Up Care; Potential Model for Patient-Led Care; Conclusion; References; Chapter 4: Detection of Recurrence: Imaging Strategies; Introduction; Current Imaging Modalities Used in Breast Cancer Survivors; Mammography; Magnetic Resonance Imaging and Ultrasound; Mammographically Occult Tumors; Imaging the Post Mastectomy Breast; Higher Risk Groups; Staging in Recurrent Disease |
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Future Directions Tomosynthesis; Oligometastatic Disease; Risk Stratified Surveillance; Conclusion; References; Chapter 5: Follow Up of Patients with Germline Mutations in High Risk Predisposition Genes; The Genetic Architecture of Breast Cancer Susceptibility; Rare, High-Penetrance Predisposition Genes; Rare, Moderate-Penetrance Predisposition Genes; Common, Low-Penetrance Predisposition Genes; Clinical Utility; Germline BRCA1 and BRCA2 Mutations and Risks of Cancer; Contralateral Breast Cancer in BRCA Carriers; Risk of Contralateral Breast Disease in BRCA Carriers |
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Impact of Contralateral Prophylactic Mastectomy Breast Screening in BRCA Carriers; Ovarian Cancer in BRCA Carriers; Ovarian Screening; Risk Reducing Bilateral Salpingo-Oophorectomy; Impact of Oophorectomy After Breast Cancer Diagnosis; Other High-Risk Predisposition Genes; Implications for Family Members; Fertility and Preimplantation Genetic Diagnosis (PGD); Cascade Testing; The Future; References; Part II: Interventions to Reduce Risk of Recurrence; Chapter 6: Endocrine Therapy; Introduction; Endocrine Therapy for the First 5 Years; Tamoxifen |
| Summary |
This book discusses the impact on women of the diagnosis and treatment of early breast cancer. Readers will learn about the risks of breast cancer recurrence and interventions to reduce these, such as endocrine therapy and bisphosphonate therapy, as well as the role of lifestyle factors such as diet and exercise. The long-term effects of treatment on fertility, the heart and other systems are discussed, as well the psychological burden for women who are increasingly likely to be cured from their cancer. Each chapter provides background and a practical guide in the management of women after the initial phase of diagnosis and treatment. Authored by a multidisciplinary team this book provides all the relevant expertise as well as different perspectives, providing a holistic picture of early breast cancer consequences. From oncologists to general practitioners as well as specialist nurses, gynaecologists, psychologists and other healthcare professionals involved in the long-term care of women with breast cancer, this book provides a timely and indispensable guide to practitioners caring for early breast cancer survivors |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Breast -- Cancer -- Patients -- Care
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Breast -- Cancer -- Treatment
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Breast Neoplasms -- prevention & control
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Neoplasm Recurrence, Local -- prevention & control
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Survivorship
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Breast Neoplasms -- complications
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Cancer Survivors
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medicines (material)
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General practice.
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Nursing.
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Oncology.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Breast -- Cancer -- Patients -- Care
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Breast -- Cancer -- Treatment
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| Form |
Electronic book
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| Author |
Ring, Alistair, editor.
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Parton, Marina, editor
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| ISBN |
9783319418582 |
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3319418580 |
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