| Description |
1 online resource : illustrations (some color) |
| Series |
Recent results in cancer research, 0080-0015 ; v. 195 |
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Recent results in cancer research ; v. 195.
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| Contents |
Part 1. Introduction -- Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer: Open Questions for Research / Michail Ignatiadis, Christos Sotiriou and Klaus Pantel -- Part 2. Minimal residual disease and breast cancer metastasis -- Self-Seeding in Cancer / Elizabeth Comen and Larry Norton -- Microenvironments Dictating Tumor Cell Dormancy / Paloma Bragado, Maria Soledad Sosa, Patricia Keely, John Condeelis and Julio A. Aguirre-Ghiso -- Part 3. Technologies for circulating tumor cell (CTC) and disseminated tumor cell (DTC) detection and characterization -- Immunomagnetic Separation Technologies / Astrid E.L.M. Hoeppener, Joost F. Swennenhuis and Leon W.M.M. Terstappen -- Microfluidic Technologies / Ali Asgar. S. Bhagat and Chwee Teck Lim -- EPISPOT Assay: Detection of Viable DTCs/CTCs in Solid Tumor Patients / Catherine Alix-Panabières -- Advances in Optical Technologies for Rare Cell Detection and Characterization / Lou Dietz and Richard Bruce -- Size-Based Enrichment Technologies for CTC Detection and Characterization / Anthony Williams, Marija Balic, Ram Datar and Richard Cote -- Emerging Technologies for CTC Detection Based on Depletion of Normal Cells / Maryam Lustberg, Kris R. Jatana, Maciej Zborowski and Jeffrey J. Chalmers -- Molecular Assays for the Detection and Characterization of CTCs / Evi S. Lianidou and Athina Markou -- Multiplex Molecular Analysis of CTCs / Anieta M. Sieuwerts and Stefanie S. Jeffrey |
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Part 4. Other blood-based biomarkers / Circulating DNA and Next-Generation Sequencing -- Susanna Cooke and Peter Campbell -- Circulating MicroRNAs as Noninvasive Biomarkers in Breast Cancer / Maria Angelica Cortez, James William Welsh and George Adrian Calin -- Circulating Endothelial Cells and Circulating Endothelial Progenitors / Patrizia Mancuso, Angelica Calleri and Francesco Bertolini -- Part 5. Disseminated tumor cells (DTCs) and circulating tumor cells (CTCs) in breast cancer clinical research and practice -- DTCs in Breast Cancer: Clinical Research and Practice / W. Janni, Brigitte Rack, N. Kasprowicz, C. Scholz and P. Hepp -- CTCs in Primary Breast Cancer (I) / Brigitte Rack, Ulrich Andergassen, Wolfgang Janni and Julia Neugebauer -- CTCs in Primary Breast Cancer (II) / E. Saloustros and D. Mavroudis -- CTCs in Metastatic Breast Cancer / Antonio Giordano and Massimo Cristofanilli -- HER2-Positive DTCs/CTCs in Breast Cancer / Andreas D. Hartkopf, Malgorzata Banys and Tanja Fehm -- DTCs/CTCs in Breast Cancer: Five Decades Later / Susan Alsamarai, Maysa M. Abu-Khalaf and Lyndsay N. Harris -- Part 6. Drug and circulating tumor cell co-development -- Challenges in Drug and Biomarker Co-Development / Sheila E. Taube and Tracy Lively -- Challenges and Opportunities in the Use of CTCs for Companion Diagnostic Development / Elizabeth A. Punnoose and Mark R. Lackner |
| Summary |
Annotation This important book provides up-to-date information on a series of topical issues relating to the approach to minimal residual disease in breast cancer patients. It first explains how the study of minimal residual disease and circulating and disseminated tumor cells (CTCs/DTCs) can assist in the understanding of breast cancer metastasis. A series of chapters then discuss the various technologies available for the detection and characterization of CTCs and DTCs, pinpointing their merits and limitations. Detailed consideration is given to the relevance of CTCs and DTCs, and their detection, to clinical research and practice. The role of other blood-based biomarkers is also addressed, and the closing chapters debate the challenges facing drug and biomarker co-development and the use of CTCs for companion diagnostic development. This book will be of interest and assistance to all who are engaged in the modern management of breast cancer |
| Analysis |
Medicine |
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Oncology |
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Gynecology |
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Cancer -- Surgery |
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Pathology |
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Medicine & Public Health |
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Surgical Oncology |
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Cancer Research |
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geneeskunde |
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volksgezondheid |
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public health |
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oncologie |
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chirurgie |
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surgery |
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neoplasms |
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pathologie |
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gynaecologie |
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gynaecology |
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Medicine (General) |
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Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references |
| Subject |
Breast -- Cancer.
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Breast -- Cancer -- Diagnosis
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Breast Neoplasms
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Neoplasm, Residual
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Neoplastic Cells, Circulating
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HEALTH & FITNESS -- Diseases -- Cancer.
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MEDICAL -- Oncology.
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Médecine.
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Breast -- Cancer
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Breast -- Cancer -- Diagnosis
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| Form |
Electronic book
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| Author |
Ignatiadis, Michail
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Sotiriou, Christos
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Pantel, Klaus
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| ISBN |
9783642281600 |
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3642281605 |
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3642281591 |
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9783642281594 |
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