| Description |
1 online resource (1 PDF file (xii, 300 pages)) : illustrations |
| Series |
Methods in molecular biology, 1064-3745 ; 2174 |
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Springer protocols |
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Methods in molecular biology (Clifton, N.J.) ; v. 2174. 1064-3745
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Springer protocols (Series) 1949-2448
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| Summary |
This fully updated edition provides the most recent advances in cancer cell signaling knowledge combined with some discussion of the current challenges and prospects in cancer therapy. Beginning with an important section on cancer resistance, the main obstacle to effective cancer therapy, the book continues with chapters exploring state-of-the-art methods in epigenetic control of cancer, metastasis promotion, as well as a variety of new technologies in the study of cancer. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls |
| Notes |
Part I: Cancer Resistance 1. Fighting Cancer Resistance: An Overview / Martha Robles-Flores 2. Prostate Cancer Spheroids: A Three-Dimensional Model for Studying Tumor Heterogeneity / Mauricio Rodríguez-Dorantes, Carlos David Cruz-Hernández, Sergio Alberto Cortés-Ramírez, Jenie Marian Cruz-Burgos, Juan Pablo Reyes-Grajeda, Oscar Peralta-Zaragoza, and Alberto Losada-García 3. Enrichment and Transcriptional Characterization of Stem Cells Isolated from Human Glioblastoma Cell Lines / Ana G. Piña-Medina, Ana M. Hernández-Vega, Nestor F. Díaz, Ismael Mancilla-Herrera, and Ignacio Camacho-Arroyo 4. Reverse Docking for the Identification of Molecular Targets of Anticancer Compounds / Angel Jonathan Ruiz-Moreno, Alexander Dömling, and Marco Antonio Velasco-Velázquez 5 |
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Mouse Model for Efficient Simultaneous Targeting of Glycolysis, Glutaminolysis, and De Novo Synthesis of Fatty Acids in Colon Cancer / Alejandro Schcolnik-Cabrera and Alfonso Dueñas-González Part II: Epigenetic Control of Cancer 6. Developing a Portable Device for the Identification of miRNAs in Fluids / Alexander Asanov, Alicia Sampieri, and Luis Vaca 7. Methods for the Study of Long Non-Coding RNA in Cancer Cell Signaling / Yi Feng, Junjie Jiang, Zhongyi Hu, Jiao Yuan, Tianli Zhang, Yutian Pan, Mu Xu, Chunsheng Li, Youyou Zhang, Lin Zhang, and Xiaowen Hu 8. RNA-Sequencing Analysis Pipeline for Prognostic Marker Identification in Cancer / Sudhanshu Shukla and Seema Khadirnaikar Part III: Metastasis Promotion 9. Correlation of Circulating Tumor Cell Measurements with 3D Quantitative Tumor Characterization to Predict Clinical Outcomes in Cancer / Sweet Ping Ng, Clifton David Fuller, and Heath Devin Skinner 10 |
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Extracellular Vesicles and Their Roles in Cancer Progression / Wen-Hsuan Chang, Richard A. Cerione, and Marc A. Antonyak 11. Analysis of Tumor-Derived Exosomes by Nanoscale Flow Cytometry / Cynthia Lopez-Pacheco, Andrea Bedoya-Lopez, Roxana Olguín-Alor, and Gloria Soldevila 12. In Vitro Models for Studying Tumor Progression / Juan Carlos González-Orozco, Saúl Gaona-Domínguez, and Ignacio Camacho-Arroyo 13. Assessment of Cell Cycle in Primitive Chronic Myeloid Leukemia Cells by Flow Cytometry after Co-Culture with Endothelial Cells Patricia Torres-Barrera, Mireya Ramírez-Florencio, and Antonieta Chávez-González Part IV: New Technologies in the Study of Cancer 14. Chimeric Antigen Receptor (CAR) T-Cell Therapy for Cancer: Challenges and Opportunities / Arimelek Cortés-Hernández, Evelyn Alvarez-Salazar, and Gloria Soldevila 15 |
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Cell-Internalization SELEX of RNA Aptamers as a Starting Point for Prostate Cancer Research / Mauricio Rodríguez-Dorantes, Sergio Alberto Cortés-Ramírez, Jenie Marian Cruz-Burgos, Juan Pablo Reyes-Grajeda, Alberto Losada-García, Vanessa González-Covarrubias, and Carlos David Cruz-Hernández 16. Generation of Functional Genetic Study Models in Zebrafish Using CRISPR-Cas9 / Francisco Carmona-Aldana, Hober N Nuñez-Martinez, Carlos A Peralta-Alvarez, Gustavo Tapia-Urzua, and Félix Recillas-Targa 17. Developing a Model for a siRNA Delivery System by Cancer Implantation into Zebrafish Circulation / Yasuhito Shimada and Mai Hazekawa 18. Fabrication of Adhesive Substrate for Incorporating Hydrogels to Investigate the Influence of Stiffness on Cancer Cell Behavior / Genaro Vázquez-Victorio, Adriana Rodríguez-Hernández, Mariel Cano-Jorge, Ana Ximena Monroy-Romero, Marina Macias-Silva, and Mathieu Hautefeuille |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL |
| Subject |
Life sciences.
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Biomechanics.
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Cancer -- Research.
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Neoplasms -- physiopathology
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Signal Transduction -- physiology
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Neoplasms -- genetics
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Biological Science Disciplines
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Biomechanical Phenomena
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biological sciences.
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Oncology.
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Sports training & coaching.
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Medical -- Oncology.
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Sports & Recreation -- General.
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Biomechanics.
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Cancer -- Research.
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Life sciences.
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| Genre/Form |
Laboratory manuals.
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Laboratory manuals.
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Manuels de laboratoire.
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| Form |
Electronic book
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| Author |
Robles-Flores, Martha, editor
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| ISBN |
9781071607596 |
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1071607596 |
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