Description |
1 online resource (xv, 227 pages) : illustrations, portraits |
Contents |
Assessing the magnitude of the problem -- The problem is growing, not going away -- Cancer through the ages -- Our current understanding -- The cancer cell-kill paradigm and its corollaries -- Chemotherapy drugs -- Treatment outcomes: dismal by any standard -- The role of the National Cancer Institute -- Publications; the facts and nothing but the facts? -- From the doctors' perspective -- From the patients' perspective -- A vision for the future -- Shifting from the cell-kill paradigm to pharmacogenomics -- Conclusions -- Glossary. =538 \\$aMode of access: World Wide Web |
Summary |
After reviewing the history of cancer and its impact on the population, Dr. Faguet exposes the antiquated notions that have driven cancer drug development, documents the stagnation in treatment outcomes despite major advances in cancer genomics and growing NCI budgets, and identifies the multiple factors that sustain the status quo. He shows that, contrary to frequent announcements of breakthroughs, our current cancer control model cannot eradicate most cancers and the reasons why. Significantly, this book also delineates a way forward via a shift from the discredited cell-kill approach of the past to an integrated, evidence-driven cancer control paradigm based on prevention, early diagnosis, and pharmacogenomics. The author's views are based on data published in mainstream scientific journals and other reliable references, 432 of which are cited |
Bibliography |
Includes bibliographical references (pages 185-208) and index |
Notes |
Print version record |
In |
Springer e-books |
Subject |
Cancer -- United States
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Neoplasms
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Neoplasms -- therapy
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Research Design
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HEALTH & FITNESS -- Diseases -- Cancer.
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Neoplasms -- United States.
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Neoplasms -- therapy -- United States.
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Research Design -- United States.
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Cancer -- United States.
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Biomédecine.
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Sciences de la vie.
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Cancer
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United States |
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United States
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Form |
Electronic book
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ISBN |
9781402036170 |
|
1402036175 |
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1402036183 |
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9781402036187 |
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1280624353 |
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9781280624353 |
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9781402086205 |
|
1402086202 |
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6610624356 |
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9786610624355 |
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