Introductory chapter -- Five Evolutionary Principles for Understanding Cancer Randolph Nesse Section 1 1. The Evolutionary Origins of Cancer and of its Control by Immune Policing and Genetic Suppression Leonard Nunney 2. Cancer Prevalence and Etiology in Wild and Captive Animals beata ujvari 3. Infection and Cancer in Nature Paul Ewald 4. Pseudohypoxia: Life at the Edge Shonagh Russell and Robert Gillies 5. The Genomic Landscape of Cancers Henry Heng 6. The Epigenetic Component in Cancer Evolution Christoph Grunau 7. Evolution of Cancer Defense Mechanisms Across Species Joshua David Schiffman 8. Coevolution of Tumor Cells and Their Microenvironment: "Niche Construction in Cancer#x94; Arig Ibrahim-Hashim and Robert Gatenby 9. Evolutionary Perspective of Tumorigenesis and Antitumor Immunity: A Comparative Approach Jacques Robert 10. The Response of Cancer Cell Populations to Therapies Jasmine Foo 11
