| Description |
1 online resource (viii, 150 pages) : illustrations |
| Contents |
1. Synaptic biochemistry -- 2. Endocytosis and exocytosis -- 3. Special proteins -- 4. Miscellaneous items -- 5. Pharmoacological implications and clinical applications -- 6. Conclusions |
| Summary |
The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a comprehensive account of our current knowledge of the neurochemical basis of synaptic plasticity. The book presents the evidence for synaptic plasticity, an account of the dendritic spine and the glutamate synapse with a focus on redox mechanisms, and the biochemical basis of the Hebbian synapse. It discusses the role of endocytosis, special proteins, and local protein synthesis. Additional topics include volume transmission, arachidonic acid signaling, hormonal modulation, and psychological stress. Finally, the book considers pharmacological and clinical implications of current research, particularly with reference to schizophrenia and Alzheimer's disease |
| Notes |
"A Bradford book." |
| Bibliography |
Includes bibliographical references (pages 107-143) and index |
| Notes |
English |
|
Print version record |
| Subject |
Neuroplasticity.
|
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Neurochemistry.
|
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Neuronal Plasticity
|
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Neurochemistry
|
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Nerve Tissue -- chemistry
|
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SOCIAL SCIENCE -- Anthropology -- Physical.
|
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Neurochemistry
|
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Neuroplasticity
|
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Neuroplasticiteit.
|
|
Eiwitten.
|
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Neuronen.
|
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Stress.
|
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Hormonen.
|
| Form |
Electronic book
|
| LC no. |
2001058700 |
| ISBN |
9780262283984 |
|
0262283980 |
|
0585442592 |
|
9780585442594 |
|
0262264676 |
|
9780262264679 |
|
