| Description |
1 online resource (439 pages) : illustrations (chiefly color) |
| Contents |
Brain function, physiology, and the blood-brain barrier -- Role of metal ions in brain function, metal transport, storage, and homeostasis -- Immune system and neuroinflammation -- Oxidative stress in neurodegenerative diseases -- Aging and mild cognitive impairment, MCI -- Parkinson's disease -- Alzheimer's disease -- Huntington's disease and polyglutamine expansion neurodegenerative diseases -- Friedreich's ataxia and diseases associated with expansion of non-coding triplets -- Creutzfeldt-Jakob and other prion diseases -- Amyotropic lateral sclerosis -- Alcoholic brain damage -- Other neurological diseases -- Therapeutic strategies to combat the onset and progression of neurological diseases |
| Summary |
Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies. Metal-based Neurodegeneration presents a detailed survey of the molecular origins of neurodegenerative diseases. Each chapter is dedicated to a specific disease, presenting the latest scient |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from electronic title page (ebrary, viewed on March 4, 2015) |
| Subject |
Nervous system -- Degeneration -- Etiology
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Brain -- Pathophysiology
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Oxidative stress.
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Metals -- Health aspects
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Neurodegenerative Diseases -- etiology
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Neurodegenerative Diseases -- metabolism
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Brain -- physiology
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Metals -- adverse effects
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Oxidative Stress
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Brain -- Pathophysiology
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Metals -- Health aspects
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Oxidative stress
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| Form |
Electronic book
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| Author |
Ward, Roberta J., author
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| ISBN |
9781118553497 |
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1118553497 |
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9781118553480 |
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1118553489 |
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9781118553503 |
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1118553500 |
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9781118553510 |
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1118553519 |
|
