Evolutionary perspective on the NPY-PYY-PP peptides and their receptors; Function, distribution and molecular pharmacology of NPY-family receptors; NPY processing in neuronal and non-neuronal tissues by proconvertases; Dipeptidyl-peptidase IV and aminopeptidase P: molecular switches of NPY/PYY receptor affinities; NPY, NPY receptors and DPPIV in innate immunity and autoimmune disorders; NPY and phagocytic cell functions; NPY in allergic and respiratory disorders; NPY analgesia: moving from acute to chronic pain
Summary
Analyzes evidence supporting the role of NPY family of peptides in regulation of the immune/inflammatory system with special reference to its medical and therapeutic implications
