Title Heat shock proteins and the brain : implications for neurodegenerative diseases and neuroprotection / edited by Alexzander A.A. Asea, Ian R. Brown

Published Dordrecht ; London : Springer, 2008

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Description 1 online resource Series Heat shock proteins ; 3 Heat shock proteins (Series) ; 3. Contents pt. 1. Heat shock proteins and neurodegenerative diseases -- pt. 2. Heat shock proteins and neuroprotection -- pt. 3. Extracellular heat shock proteins and the nervous system -- pt. 4. Aging, control of life span and expression of heat shock proteins Summary With the prevalence of neurodegenerative diseases on the rise as average life expectancy increases, the hunt for effective treatments and preventive measures for these disorders is a pressing challenge. Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis have been termed 'protein misfolding disorders' that are characterized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a therapeutic strategy to counter conformational changes in neural Bibliography Includes bibliographical references and index Notes Print version record Subject Heat shock proteins. Nervous system -- Degeneration. Neuroprotective agents. Nerve tissue proteins. Heat-Shock Proteins -- therapeutic use Heat-Shock Proteins -- metabolism Nerve Tissue Proteins Neurodegenerative Diseases -- drug therapy Neuroprotective Agents -- pharmacology Heat-Shock Proteins Neuroprotective Agents Biomédecine. Sciences de la vie. Heat shock proteins Nerve tissue proteins Nervous system -- Degeneration Neuroprotective agents Form Electronic book Author Asea, Alexzander A. A Brown, Ian R ISBN 9781402082313 1402082312 1402082304 9781402082306

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