| Description |
1 online resource |
| Contents |
Intro; Preface to the Second Edition; Preface to the First Edition; Contents; List of Figures; List of Tables; Abbreviations; Author's Biography; Chapter 1: Introduction; Definitions; Historical Development of Neuroprotection; Neurophysiological Basis of Neuroprotection; Astrocytic Glycogen-Derived Lactate as Fuel for the Brain; Gene Expression in the Human Brain; Role of Astrocytes in Neuroprotection; Role of Glymphatic System in Neuroprotection; Role of Sleep in Neuroprotection; Role of Cerebral Metabolism in Neuroprotection; Role of Circadian Genes in Neuroprotection |
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Rai Adaptor ProteinStem Cell Factor; Role of the Immune System in Neuroprotection; Induction of DNA Repair Enzymes for Neuroprotection; Microtubule-Based Neuroprotective Response to Axonal Injury; Pathomechanisms of CNS Injury as Basis for Neuroprotection; Biomarkers of Neurological Disorders and Neuroprotection; CNS Biomarker Identification Using Proteomics; Brain Imaging for Detection of Biomarkers; Neuroprotection in Cerebral Hypoxia; Effects of Hypoxia on the Brain; Cerebral Metabolism During Hypoxia; Adaptive Mechanisms in Hypoxia; Neuroprotection in Hypoxia-Ischemia |
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Neuroprotection in NeuroinflammationBiomarkers of Neuroinflammation; Neuroprotection in Mental Stress; Role of Neuroprotection in Various Neurological Disorders; Neuroprotection and Neuroregeneration; Acute Versus Chronic Neuroprotection; Discovery and Evaluation of Neuroprotective Agents; Neuroprotective Drug Discovery; Discovery of CNS Drugs That Penetrate the Blood-Brain Barrier; In Vitro Assays for the Evaluation of Neuroprotective Agents; Oxidative Injury Model to Test Neuroprotective Drugs; Apoptosis Model for Designing Neuroprotective Drugs |
| Summary |
This fully revised edition explores the management of neurological disorders with a focus on neuroprotection, disease modification, and neuroregeneration rather than symptomatic treatment. Since the publication of the first edition, advances in biotechnology, particularly in cell and gene therapies, are reflected in this volume, as are numerous new and repurposed drugs in clinical trials. Overall, The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of disorders of the central nervous system |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from digital title page (viewed on June 20, 2019) |
| Subject |
Neuroprotective agents -- Handbooks, manuals, etc
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Nervous System Diseases -- drug therapy
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Neuroprotective Agents -- therapeutic use
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Neuroprotective agents
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| Genre/Form |
Electronic books
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| Form |
Electronic book
|
| Genre/Form |
handbooks.
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Handbooks and manuals
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Handbooks and manuals.
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Guides et manuels.
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| ISBN |
9781493994656 |
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1493994654 |
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1493994646 |
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9781493994649 |
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