| Description |
1 online resource |
| Series |
Neurology--laboratory and clinical research development series |
|
Neurology--laboratory and clinical research development series.
|
| Contents |
ALUMINUM NEUROTOXICITY FROM SUBTLE MOLECULAR LESIONS TO NEUROLOGICAL DISEASES ; ALUMINUM NEUROTOXICITY FROM SUBTLE MOLECULAR LESIONS TO NEUROLOGICAL DISEASES ; CONTENTS ; PREFACE; Chapter 1 MECHANISTIC ASPECTS OF ALUMINIUM NEUROTOXICITY: OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTIONS ; ABSTRACT ; INTRODUCTION ; NEUROTOXICITY OF ALUMINIUM ; Oxidative Stress in Aluminium Neurotoxicity ; Mitochondrial Oxidative Stress and Dysfunction in Aluminium Neurotoxicity ; Impaired Mitochondrial Energy Metabolism and Oxidative Phosphorylation ; Dysregulated Calcium (Ca2+) Homeostasis |
|
Mitochondria Mediated Apoptosis in Aluminum Neurotoxicity CONCLUSION; REFERENCES ; Chapter 2 ALUMINIUM AND IMBALANCE IN NEUROTRANSMITTER RELEASE ; ABSTRACT ; ABBREVIATIONS; INTRODUCTION ; ALUMINIUM-RELATED NEUROPATHIES ; ALUMINIUM INTERFERES WITH GASEOUS NEUROTRANSMISSION ; Aluminium and H2S Signalling ; Aluminium and CO Synthesis; Aluminium and Nitroxidergic Neurons ; REVERSAL OF PLASMA MEMBRANE NEUROTRANSMITTER TRANSPORTERS IS DYSREGULATED BY ALUMINIUM ; Aluminium and Neurotransmitter Transporters ; Aluminium Effect on Sodium-Dependent Transport of Neurotransmitters |
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Aluminium Effect on Modulators of Neurotransmitter Transporters Aluminium Effect on Na/K-ATPase and Neurotransmitter Release ; ALUMINIUM REDUCES SNARE-MEDIATED, CALCIUM-DEPENDENT EXOCYTOSIS ; Aluminium Effect on Presynaptic Calcium and Neurosecretion ; Aluminium and the Fusion Pore Properties ; CONCLUSION ; REFERENCES ; Chapter 3 THE RISK OF ALUMINIUM NEUROTOXICITY FOR YOUNG ANIMALS AND HUMANS DUE TO MULTIPLE EXPOSURE OPPORTUNITIES, PARTICULARLY PERINATAL ; ABSTRACT ; INTRODUCTION ; MATERIALS AND METHODS ; Animals ; Experimental Design for Al Treatments |
|
Physical Assessment during Weaning Period Body Weight ; Eye Opening and Hair Appearance ; Neuromotor Maturation Assessment during Weaning Period ; Righting Reflex ; Cliff Avoidance ; Rotating Reflex ; Cognitive Behavioral Assessment ; Active Avoidance Responses ; Morris Water-Maze Test ; Biochemical Studies ; Determination of Monoamines ; Determination of Nonenzymatic OS Indices ; Lipid Peroxides ; Glutathione ; Determination of Enzymatic OS Indices ; Glutathione-S-Transferase ; Catalase ; Superoxide Dismutase ; Statistical Analysis ; RESULTS ; Physical Assessment during Weaning Period |
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Behavioral Studies Neuromotor Maturation ; Active Avoidance Test ; Morris Water-Maze Task ; Biochemical Studies ; Levels of Monoamines in Forebrain ; Levels of Nonenzymatic OS Indices ; Levels of Enzymatic OS Indices ; DISCUSSION ; CONCLUSION ; ACKNOWLEDGMENT ; REFERENCES; Chapter 4 THE PROTECTIVE AND DOSE-DEPENDENT EFFECTS OF L-NAME IN ALUMINIUM-INDUCED NEUROTOXICITY ; ABSTRACT ; ABBREVIATIONS; INTRODUCTION; NITRIC OXIDE ; Nitric Oxide Synthesis ; Nitric Oxide Actions ; NITRIC OXIDE: MITOCHONDRIA AND GLYCOLYSIS ; THE REACTIVE NITROGEN SPECIES AND NITROSATIVE STRESS |
| Notes |
Includes index |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource, title from PDF title page (Ebsco, viewed on August 31, 2016) |
| Subject |
Aluminum -- Toxicology
|
|
Aluminum -- Physiological effect.
|
|
Neurotoxicology.
|
|
Neurotoxicity Syndromes
|
|
MEDICAL / Pharmacology
|
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Aluminum -- Physiological effect
|
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Aluminum -- Toxicology
|
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Neurotoxicology
|
| Form |
Electronic book
|
| Author |
Jelenković, Ankica, editor.
|
| LC no. |
2020679336 |
| ISBN |
9781634847629 |
|
1634847628 |
|
