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Title Isoquinolines and beta-carbolines as neurotoxins and neuroprotectants : new vistas In Parkinson's disease therapy / Lucyna Antkiewicz-Michaluk, Hans Rommelspacher, editors
Published New York : Springer, ©2012

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Description 1 online resource (x, 177 pages)
Series Current Topics in Neurotoxicity Ser
Current Topics in Neurotoxicity Ser
Contents 880-01 Two faces of 1,2,3,4-tetrahydroisoquinoline mode of action in the mammalian brain: is it an endogenous neurotoxin or a neuromodulator? -- Isoquinolines as a neurotoxins: action and molecular mechanism -- 1-Methyl-1,2,3,4-tetrahydroisoquinoline -- a potent neuroprotecting agent -- 1-Methyl-1,2,3,4-tetrahydroisoquinoline and addiction: experimental studies -- Beta-carbolines as neurotoxins -- Neuroprotective?-carbolines: occurrence, formation and biodegradation -- Beta-carbolines and neuroprotection: inhibition of monoamine oxidase -- Beta-carbolines increase the efficiency of the respiratory chain in mitochondria -- Antioxidant properties of?-carbolines -- Restoration of neuronal functions in damaged dopamine neurons: in vitro and in vivo studies -- Prospects for new treatment options in neurodegenerative diseases
880-01/(S Two faces of 1,2,3,4-tetrahydroisoquinoline mode of action in the mammalian brain: is it an endogenous neurotoxin or a neuromodulator-- Isoquinolines as a neurotoxins: action and molecular mechanism -- 1-Methyl-1,2,3,4-tetrahydroisoquinoline -- a potent neuroprotecting agent -- 1-Methyl-1,2,3,4-tetrahydroisoquinoline and addiction: experimental studies -- Beta-carbolines as neurotoxins -- Neuroprotective β-carbolines: occurrence, formation and biodegradation -- Beta-carbolines and neuroprotection: inhibition of monoamine oxidase -- Beta-carbolines increase the efficiency of the respiratory chain in mitochondria -- Antioxidant properties of β-carbolines -- Restoration of neuronal functions in damaged dopamine neurons: in vitro and in vivo studies -- Prospects for new treatment options in neurodegenerative diseases
Summary Annotation This work reports results from behavioural, neurochemical and molecular experiments which demonstrate a range of TIQs and BCs effects - from their rather mild neurotoxic actions to the important neuroprotective and antiaddictive properties
Analysis Medicine
Neurosciences
Neurochemistry
Pharmacy
Biomedicine
Bibliography Includes bibliographical references and index
Subject Neurochemistry.
Isoquinoline.
Parkinson's disease -- Chemotherapy.
Neurotoxic agents.
Neuroprotective agents.
Carbolines.
Parkinson's disease.
Symptomatic Parkinson's disease.
Neurochemistry
Neurotoxins
Neuroprotective Agents
Isoquinolines
Carbolines
Parkinson Disease
Parkinson Disease, Secondary
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Isoquinoline.
Neurochemistry.
Parkinson's disease -- Chemotherapy.
Form Electronic book
Author Antkiewicz-Michaluk, Lucyna.
Rommelspacher, Hans
ISBN 9781461415428
146141542X
9781489987549
1489987541