Limit search to available items
Book Cover

Title Fundamental neuropathology for pathologists and toxicologists : principles and techniques / [edited] by Brad Bolon, Mark T. Butt
Published Hoboken, N.J. : John Wiley & Sons, ©2011


Description 1 online resource
Contents Fundamentals of Neurobiology. Fundamental Neuropathology for Pathologists and Toxicologists: An Introduction / Brad Bolon, Doyle G Graham -- Functional Neuroanatomy / Michael H Stoffel, Anna Oevermann, Marc Vandevelde -- Atlas of Comparative Neuroanatomy / Anna Oevermann, Marc Vandevelde, Michael H Stoffel -- Principles of Comparative and Correlative Neurodevelopment and Their Implications for Developmental Neurotoxicity / Brad Bolon -- Localizing Neuropathological Lesions Using Neurological Findings / Brad Bolon, Dennis O'Brien -- Behavioral Model Systems for Evaluating Neuropathology / Virginia C Moser -- Cognitive Assessments in Nonhuman Primates / Tucker A Patterson, Merle G Paule -- Impact of Aging on Brain Structure and Function in Rodents and Canines / M Paul Murphy, Elizabeth Head -- Fundamentals of Neurotoxicity Detection / Robert C Switzer -- Toxicologic Neuropathology: Methodology. Practical Neuropathology of the Rat and Other Species / William H Jordan, Greg Hall, Monty J Hyten, Jamie K Young -- Fluoro-Jade Dyes: Fluorochromes for the Histochemical Localization of Degenerating Neurons / Sumit Sarkar, Larry Schmued -- Histological Markers of Neurotoxicity (Nonfluorescent) / Robert C Switzer, Mark T Butt -- Common Histological Artifacts in Nervous System Tissues / Robert H Garman -- High-Definition Microscopic Analysis of the Nervous System / Bernard S Jortner -- Stereological Solutions for Common Quantitative Endpoints in Neurotoxicology / Rogely Waite Boyce, Karl-Anton Dorph-Petersen, Lise Lyck, Hans J̜rgen G Gundersen -- Anatomy and Processing of Peripheral Nerve Tissues / William Valentine, Brad Bolon -- Pathology Methods in Nonclinical Neurotoxicity Studies: Evaluation of Muscle / Beth A Valentine, John W Hermanson -- Toxicologic Neuropathology: Methodology. In Vivo Imaging Applications for the Nervous System in Animal Models / Kathy Gabrielson, Craig Fletcher, Paul W Czoty, Michael A Nader, Tracy Gluckman -- Cerebrospinal Fluid Analysis in Toxicological Neuropathology / William Vernau, Karen M Vernau, Brad Bolon -- Molecular Techniques in Toxicological Neuropathology / Arun R Pandiri, Stephanie A Lahousse, Robert C Sills -- Toxicological Neuropathology: Current Practices. Evaluation of the Adult Nervous System in Preclinical Studies / Mark T Butt -- Toxicologic Neuropathology: Methodology. Pathology Methods in Nonclinical Neurotoxicity Studies: The Developing Central Nervous System / Wolfgang Kaufmann -- Toxicological Neuropathology: Current Practices. Neuropathological Analysis of the Peripheral Nervous System / Georg J Krinke -- Toxicological Pathology of the Retina and Optic Nerve / Meg Ramos, Christopher M Reilly, Brad Bolon -- Toxicological Neuropathology of the Ear / Andrew Forge, Ruth Taylor, Brad Bolon -- Neuropathology of the Olfactory System / Mary Beth Genter, Brad Bolon -- Applied Toxicological Neuropathology. Spinal Delivery and Assessment of Drug Safety / Tony L Yaksh -- Diagnostic Neuropathology / Ana Alcaraz, Mark T Butt -- Toxicological Neuropathology in Medical Practice / Thomas J Montine, Douglas C Anthony -- Toxicological Neuropathology in Veterinary Practice / Peter B Little, David C Dorman -- Regulatory Considerations in Toxicological Neuropathology / Karl F Jensen, Kathleen C Raffaele -- The Neuropathology Report and the Neuropathology Peer Review Report / Mark T Butt -- Preparation of Personnel for Performing Neuropathological Assessment / Jamie K Young, Mary Jeanne Kallman -- Regulatory Guide to the Histopathological Assessment of Neurotoxicity Studies / Hope Salvo, Mark T Butt -- Toxicological Neuropathology: The Next Two Decades / Brad Bolon, Mark T Butt -- Appendixes: Ready References of Neurobiology Knowledge -- Appendix 2: Text-Based Neuroanatomic Atlases for Toxicological Neuropathology Studies -- Appendix 3: Text-Based Neurobiology References for Toxicological Neuropathologists -- Appendix 4: Web-Based Neurobiology References for Toxicological Neuropathologists -- Appendix 5: Toxicological Neuropathology References for Nervous System Targets -- Appendix 6: Comparative and Correlative Neurobiological Parameters for the Brain -- Appendix 7: Comparison of Relative Proportions in the Brain and Spinal Cord Regions of Humans and Rats -- Appendix 8: Chemical Composition of Central Nervous System Tissues and Fluids
Summary This book offers pathologists, toxicologists, other medical professionals, and students an introduction to the discipline and techniques of neuropathology - including chemical and environmental, biological, medical, and regulatory details important for performing an analysis of toxicant-induced neurodiseases. In addition to a section on fundamentals, the book provides detailed coverage of current practices (bioassays, molecular analysis, and nervous system pathology) and practical aspects (data interpretation, regulatory considerations, and tips for preparing reports)
Bibliography Includes bibliographical references
Notes English
Print version record
Subject Neurotoxicology.
Nervous system -- Diseases
Neurotoxicity Syndromes -- diagnosis
Neurotoxicity Syndromes -- physiopathology
Models, Animal
Nervous System -- drug effects
Neurotoxins -- adverse effects
Nervous System Diseases
HEALTH & FITNESS -- Diseases -- Nervous System (incl. Brain)
MEDICAL -- Neurology.
Nervous system -- Diseases.
Health & Biological Sciences.
Form Electronic book
Author Bolon, Brad.
Butt, Mark T
LC no. 2010033335
ISBN 9780470939956