| Description |
1 online resource |
| Contents |
Fundamentals of Neurobiology. Fundamental Neuropathology for Pathologists and Toxicologists: An Introduction / Brad Bolon, Doyle G Graham -- Functional Neuroanatomy / Michael H Stoffel, Anna Oevermann, Marc Vandevelde -- Atlas of Comparative Neuroanatomy / Anna Oevermann, Marc Vandevelde, Michael H Stoffel -- Principles of Comparative and Correlative Neurodevelopment and Their Implications for Developmental Neurotoxicity / Brad Bolon -- Localizing Neuropathological Lesions Using Neurological Findings / Brad Bolon, Dennis O'Brien -- Behavioral Model Systems for Evaluating Neuropathology / Virginia C Moser -- Cognitive Assessments in Nonhuman Primates / Tucker A Patterson, Merle G Paule -- Impact of Aging on Brain Structure and Function in Rodents and Canines / M Paul Murphy, Elizabeth Head -- Fundamentals of Neurotoxicity Detection / Robert C Switzer -- Toxicologic Neuropathology: Methodology. Practical Neuropathology of the Rat and Other Species / William H Jordan, Greg Hall, Monty J Hyten, Jamie K Young -- Fluoro-Jade Dyes: Fluorochromes for the Histochemical Localization of Degenerating Neurons / Sumit Sarkar, Larry Schmued -- Histological Markers of Neurotoxicity (Nonfluorescent) / Robert C Switzer, Mark T Butt -- Common Histological Artifacts in Nervous System Tissues / Robert H Garman -- High-Definition Microscopic Analysis of the Nervous System / Bernard S Jortner -- Stereological Solutions for Common Quantitative Endpoints in Neurotoxicology / Rogely Waite Boyce, Karl-Anton Dorph-Petersen, Lise Lyck, Hans J̜rgen G Gundersen -- Anatomy and Processing of Peripheral Nerve Tissues / William Valentine, Brad Bolon -- Pathology Methods in Nonclinical Neurotoxicity Studies: Evaluation of Muscle / Beth A Valentine, John W Hermanson -- Toxicologic Neuropathology: Methodology. In Vivo Imaging Applications for the Nervous System in Animal Models / Kathy Gabrielson, Craig Fletcher, Paul W Czoty, Michael A Nader, Tracy Gluckman -- Cerebrospinal Fluid Analysis in Toxicological Neuropathology / William Vernau, Karen M Vernau, Brad Bolon -- Molecular Techniques in Toxicological Neuropathology / Arun R Pandiri, Stephanie A Lahousse, Robert C Sills -- Toxicological Neuropathology: Current Practices. Evaluation of the Adult Nervous System in Preclinical Studies / Mark T Butt -- Toxicologic Neuropathology: Methodology. Pathology Methods in Nonclinical Neurotoxicity Studies: The Developing Central Nervous System / Wolfgang Kaufmann -- Toxicological Neuropathology: Current Practices. Neuropathological Analysis of the Peripheral Nervous System / Georg J Krinke -- Toxicological Pathology of the Retina and Optic Nerve / Meg Ramos, Christopher M Reilly, Brad Bolon -- Toxicological Neuropathology of the Ear / Andrew Forge, Ruth Taylor, Brad Bolon -- Neuropathology of the Olfactory System / Mary Beth Genter, Brad Bolon -- Applied Toxicological Neuropathology. Spinal Delivery and Assessment of Drug Safety / Tony L Yaksh -- Diagnostic Neuropathology / Ana Alcaraz, Mark T Butt -- Toxicological Neuropathology in Medical Practice / Thomas J Montine, Douglas C Anthony -- Toxicological Neuropathology in Veterinary Practice / Peter B Little, David C Dorman -- Regulatory Considerations in Toxicological Neuropathology / Karl F Jensen, Kathleen C Raffaele -- The Neuropathology Report and the Neuropathology Peer Review Report / Mark T Butt -- Preparation of Personnel for Performing Neuropathological Assessment / Jamie K Young, Mary Jeanne Kallman -- Regulatory Guide to the Histopathological Assessment of Neurotoxicity Studies / Hope Salvo, Mark T Butt -- Toxicological Neuropathology: The Next Two Decades / Brad Bolon, Mark T Butt -- Appendixes: Ready References of Neurobiology Knowledge -- Appendix 2: Text-Based Neuroanatomic Atlases for Toxicological Neuropathology Studies -- Appendix 3: Text-Based Neurobiology References for Toxicological Neuropathologists -- Appendix 4: Web-Based Neurobiology References for Toxicological Neuropathologists -- Appendix 5: Toxicological Neuropathology References for Nervous System Targets -- Appendix 6: Comparative and Correlative Neurobiological Parameters for the Brain -- Appendix 7: Comparison of Relative Proportions in the Brain and Spinal Cord Regions of Humans and Rats -- Appendix 8: Chemical Composition of Central Nervous System Tissues and Fluids |
| Summary |
This book offers pathologists, toxicologists, other medical professionals, and students an introduction to the discipline and techniques of neuropathology - including chemical and environmental, biological, medical, and regulatory details important for performing an analysis of toxicant-induced neurodiseases. In addition to a section on fundamentals, the book provides detailed coverage of current practices (bioassays, molecular analysis, and nervous system pathology) and practical aspects (data interpretation, regulatory considerations, and tips for preparing reports) |
| Bibliography |
Includes bibliographical references |
| Notes |
English |
|
Print version record |
| Subject |
Neurotoxicology.
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Nervous system -- Diseases
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Neurotoxicity Syndromes -- diagnosis
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Neurotoxicity Syndromes -- physiopathology
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Models, Animal
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Nervous System -- drug effects
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Neurotoxins -- adverse effects
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Nervous System Diseases
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HEALTH & FITNESS -- Diseases -- Nervous System (incl. Brain)
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MEDICAL -- Neurology.
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Nervous system -- Diseases
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Neurotoxicology
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Medicine.
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Health & Biological Sciences.
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Neurology.
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| Form |
Electronic book
|
| Author |
Bolon, Brad.
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Butt, Mark T
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| LC no. |
2010033335 |
| ISBN |
9780470939956 |
|
0470939958 |
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9780470939949 |
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047093994X |
|
1283239450 |
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9781283239455 |
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9781118002230 |
|
1118002237 |
|
9786613239457 |
|
6613239453 |
|
