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Title Secretory systems and toxins edited by Michal Linial, Alfonso Grasso, and Philip Lazarovici
Published Amsterdam : Harwood Academic Publishers, c1998

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Description 1 online resource (xvi, 476 p. :) ill. (some col.)
Series Cellular and molecular mechanisms of toxin action, v. 2
Cellular and molecular mechanisms of toxin action ; v. 2.
Contents Synaptic vesicle proteins: a molecular study / William S. Trimble -- Synaptic vesicle proteins: a genetic approach / Nils Brose -- Dissection of the secretory machinery / Lorenzo L. Pellegrini ... [et al.] -- Vesicular trafficking on the late secretory pathway in the budding yeast, S. Cerevisiae: yeast as a genetic tool in which to explore protein export / Jeffrey E. Gerst -- Regulatory roles for lipids in vesicle trafficking and secretion / Anthony H. Futerman and Mordechai Liscovitch -- Fusion proteins and the fusion events / Manfred Lindau -- Tetanus toxin as a valuable pharmacological tool for studying polysialogangliosides in neuronal signal transduction / Philip Lazarovici -- Molecular mechanisms of the action of Clostridium botulinum Type B neurotoxin / Shunji Kozaki ... [et al.] -- [alpha]-Latrotoxin receptors / Alexander G. Petrenko and Valery G. Krasnoperov -- Neurotoxins and safety-latches of the secretory process / Michal Linial -- Bacterial neurotoxins in invertebrates: Aplysia and the deciphering of the mode of action of Clostridial neurotoxins / Frederic Doussau, Florence Deloye and Bernard Poulain
(Continued) Chromaffin cells as a secretory system: the use of neurotoxins / Barbara Hohne-Zell and Manfred Gratzl -- External ions and [alpha]-Latrotoxin action / Zoltan Deri and Vera Adam-Vizi -- Botulinum neurotoxins and their substrates / Judit Herreros and Juan Blasi -- Clostridial neurotoxins as enzymes: structure and function / Cesare Montecucco ... [et al.] -- Purification, function and selectivity in [alpha]-Latrotoxin / Alfonso Grasso ... [et al.] -- Neurotoxins, cytoskeletons and calcium channels: functional studies at mammalian synapses formed in culture / Sumiko Mochida -- The synapsins and neurotransmission / Flavia Valtorta, Fabio Benfenati and Chiara Leoni -- Morphological studies of the secretory machinery using neurotoxin probes / Claudia Verderio, Silvia Coco and Michela Matteoli -- Membrane fusion protein Annexin VII: a Ca[superscript 2+]-activated GTPase target for Mastoparan in secreting Chromaffin cells / Hung Caohuy, Meera Srivastava and Harvey B. Pollard
Summary "This volume deals with the relationships between toxins and one of the most fundamental processes in any living cell - the secretory cycle. The reader will find up-to-date information on secretion, generated by experts in this fast evolving field. In the last decade extensive molecular and cellular studies have exposed the molecular similarity among most known secretory systems. In this book secretion is discussed from its basic mode found in yeast up to its most sophisticated version in neurotransmitter release in nerve terminals. A comprehensive view on the mode of action of toxins which block secretion but also those which cause hyper-activation of exocytosis is provided. This book addresses the issues of toxin's action by deciphering the molecular and cellular basis of exocytosis in various organisms and cellular contents."--BOOK JACKET. "This volume contains useful information for students, clinicians and researchers who are interested in the involvement of toxins in secretion."--BOOK JACKET
Bibliography Includes bibliographical references and index
Subject Secretion.
Toxins.
Neurotoxic agents.
Neurotoxins -- metabolism
Neurotransmitter Agents -- metabolism
Bodily Secretions
Toxins, Biological
Neurotoxic agents.
Secretion.
Toxins.
Form Electronic book
Author Linial, Michal
Grasso, Alfonso
Lazarovici, Philip
ISBN 9789057023354
9057023350