Description 
1 online resource (xii, 431 pages) : illustrations 
Series 
Probability and its applications 

Springer series in statistics. Probability and its applications.

Contents 
Basic models  Estimation and hypothesis testing  Recombination  Population complications  Stepping stone model  Natural selection  Diffusion process  Multidimensional diffusions  Genome rearrangement 
Summary 
How is genetic variability shaped by natural selection, demographic factors, and random genetic drift? To approach this question, we introduce and analyze a number of probability models beginning with the basics, and ending at the frontiers of current research. Throughout the book, the theory is developed in close connection with examples from the biology literature that illustrate the use of these results. Along the way, there are many numerical examples and graphs to illustrate the conclusions. This is the second edition and is twice the size of the first one. The material on recombination and the stepping stone model have been greatly expanded, there are many results form the last five years, and two new chapters on diffusion processes develop that viewpoint. This book is written for mathematicians and for biologists alike. No previous knowledge of concepts from biology is assumed, and only a basic knowledge of probability, including some familiarity with Markov chains and Poisson processes. The book has been restructured into a large number of subsections and written in a theoremproof style, to more clearly highlight the main results and allow readers to find the results they need and to skip the proofs if they desire. Rick Durrett received his Ph. D. in operations research from Stanford University in 1976. He taught in the UCLA mathematics department before coming to Cornell in 1985. He is the author of eight books and 160 research papers, most of which concern the use of probability models in genetics and ecology. He is the academic father of 39 Ph. D. students and was recently elected to the National Academy of Sciences 
Notes 
Previous edition: 2002 
Bibliography 
Includes bibliographical references (pages 399426) and index 
Notes 
English 

Print version record 
Subject 
Evolutionary genetics  Statistical methods


Nucleotide sequence  Statistical methods


Probabilities.


Variation (Biology)  Statistical methods


Molecular evolution.


Evolution, Molecular


Models, Genetic


Base Sequence


Probability


probability.


SCIENCE  Life Sciences  Molecular Biology.


Nucleotide sequence  Statistical methods.


Probabilities.


Variation (Biology)  Statistical methods.


Evolutionary genetics  Statistical methods.


Molecular evolution.


Evolutionary genetics  Statistical methods.


Nucleotide sequence  Statistical methods.


Probabilities.


Variation (Biology)  Statistical methods.

Form 
Electronic book

ISBN 
9780387781693 

0387781692 

6611954236 

9786611954239 
