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Author Korpelainen, Eija, author.

Title RNA-seq data analysis : a practical approach / Eija Korpelainen, Jarno Tuimala, Panu Somervuo, Mikael Huss, Garry Wong
Published Boca Raton : CRC Press, Taylor & Francis Group, [2015]
Online access available from:
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Description 1 online resource (xxiv, 298 pages) : illustrations
Series Chapman & Hall/CRC mathematical and computational biology series
Chapman and Hall/CRC mathematical & computational biology series.
Contents Chapter 1. Introduction to RNA-seq -- chapter 2. Introduction to RNA-seq data analysis -- chapter 3. Quality control and preprocessing -- chapter 4. Aligning reads to reference -- chapter 5. Transcriptome assembly -- chapter 6. Quantitation and annotation-based quality control -- chapter 7. RNA-seq analysis framework in R and bioconductor -- chapter 8. Differential expression analysis -- chapter 9. Analysis of differential exon usage -- chapter 10. Annotating the results -- chapter 11. Visualization -- chapter 12. Small noncoding RNAs -- chapter 13. Computational analysis of small noncoding RNA sequencing data
Summary "RNA-seq offers unprecedented information about transcriptome, but harnessing this information with bioinformatics tools is typically a bottleneck. This self-contained guide enables researchers to examine differential expression at gene, exon, and transcript level and to discover novel genes, transcripts, and whole transcriptomes. Each chapter starts with theoretical background, followed by descriptions of relevant analysis tools. The book also provides examples using command line tools and the R statistical environment. For non-programming scientists, the same examples are covered using open source software with a graphical user interface"--Provided by publisher
Analysis bioinformatics
data analysis
nucleotide sequences
Genome informatics
Nucleic Acids
Notes "A Chapman & Hall book."
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Sequence Analysis, RNA -- methods.
Statistics as Topic.
Nucleotide sequence -- Data processing.
Nucleotide sequence -- Statistical methods
Nucleotide sequence -- Data processing.
Nucleotide sequence -- Statistical methods.
SCIENCE -- Life Sciences -- Biochemistry.
Form Electronic book
Author Huss, Mikael, author.
Somervuo, Panu, author.
Tuimala, Jarno, author.
Wong, Garry, author.
ISBN 1466595019