| Description |
1 online resource (x, 400 pages) : illustrations (some color) |
| Series |
Methods in molecular biology, 1940-6029 ; 1706 |
|
Methods in molecular biology (Clifton, N.J.) ; v. 1706. 1064-3745
|
| Contents |
Identification of disease susceptibility alleles in the next generation sequencing era / Johanna K. DiStefano and Christopher B. Kingsley -- Induced pluripotent stem cells in disease modeling and gene identification / Satish Kumar, John Blangero, and Joanne E. Curran -- Development of targeted therapies based on gene modification / Taylor M. Benson, Fatjon Leti, and Johanna K. DiStefano -- What can we learn about human disease from the nematode C. elegans / Javier Apfeld and Scott Alper -- Microbiome sequencing methods for studying human diseases / Rebecca M. Davidson and L. Elaine Epperson -- Emerging role of long noncoding RNAs in human disease / Johanna K. DiStefano -- Identification of disease-related genes using a genome-wide association study approach / Tobias Wohland and Dorit Schleinitz -- Whole genome library construction for next generation sequencing / Jonathan J. Keats, Lori Cuyugan, Jonathan Adkins, and Winnie S. Liang -- Whole exome library construction for next generation sequencing / Winnie S. Liang, Kristi Stephenson, Jonathan Adkins, Austin Christofferson, Adrienne Helland, Lori Cuyugan, and Jonathan J. Keats -- Optimized methodology for the generation of RNA-sequencing libraries from low-input starting material : enabling analysis of specialized cell types and clinical samples / Kendra Walton and Brian P. O'Connor -- Using fluidigm C1 to generate single-cell full-length cDNA libraries for mRNA sequencing / Robert Durruthy-Durruthy and Manisha Ray -- MiSeq : a next generation sequencing platform for genomic analysis / Rupesh Kanchi Ravi, Kendra Walton, and Mahdieh Khosroheidari -- Methods for CpG methylation array profiling via bisulfite conversion / Fatjon Leti, Lorida Llaci, Ivana Malenica, and Johanna K. DiStefano -- miRNA quantification method using quantitative polymerase chain reaction in conjunction with Cq method / Fatjon Leti and Johanna K. DiStefano -- Primary airway epithelial cell gene editing using CRISPR-Cas9 / Jamie L. Everman, Cydney Rios, and Max A. Seibold -- RNA interference to knock down gene expression / Haiyong Han -- Using luciferase reporter assays to identify functional variants at disease-associated loci / Anup K. Nair and Leslie J. Baier -- Physiologic interpretation of GWAS signals for type 2 diabetes / Richard M. Watanabe -- Identification of Genes for Hereditary Hemochromatosis / Glenn S. Gerhard, Barbara V. Paynton, and Johanna K. DiStefano -- Identification of driver mutations in rare cancers : the role of SMARCA4 in small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) / Jessica D. Lang and William P.D. Hendricks -- Rise and fall and rise of linkage analysis as a technique for finding and characterizing inherited influences on disease expression / Ettie M. Lipner and David A. Greenberg |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Disease susceptibility.
|
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Genetics -- Technique.
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Genetic screening.
|
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Disease Susceptibility
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Genotype
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Genetic Phenomena
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Genetic Predisposition to Disease
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Genetic Techniques
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Pathologic Processes
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Pathological Conditions, Signs and Symptoms
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Genetic Association Studies
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Genetic Testing
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Medical genetics.
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Medical -- Genetics.
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Disease susceptibility
|
| Genre/Form |
Laboratory manuals.
|
|
Manuels de laboratoire.
|
| Form |
Electronic book
|
| Author |
DiStefano, Johanna K., author
|
| ISBN |
9781493974719 |
|
1493974718 |
|
9781493974702 |
|
149397470X |
|
