| Description |
1 online resource (207 pages) |
| Contents |
Intro -- Preface -- Acknowledgments -- Contents -- About the Editors -- 1: The Normal Thymus -- 1.1 Embryology -- 1.2 Normal and Ectopic Location of the Thymus -- 1.3 Macroscopy -- 1.4 Histology -- 1.5 Thymic Function -- 1.6 Thymic Involution -- References -- 2: Immunohistochemistry of Normal Thymus -- 2.1 Introduction -- 2.2 Markers of the Epithelial Component -- 2.2.1 Cytoplasmic Markers -- 2.2.1.1 Cytokeratins -- 2.2.2 Nuclear Markers -- 2.2.2.1 p63 and p40 -- 2.2.2.2 PAX8 -- 2.2.3 Other Markers -- 2.2.3.1 Glut-1 -- 2.2.4 Immune Checkpoint Inhibitors |
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2.2.5 Compartment-Specific Antibodies -- 2.2.6 FoxN1 and CD205 -- 2.2.6.1 FoxN1 -- 2.2.6.2 CD205 -- 2.3 Markers of the Lymphoid Component -- 2.3.1 CD3 -- 2.3.2 CD4 and CD8 -- 2.3.3 CD5 -- 2.3.4 CD10 -- 2.3.5 CD1a -- 2.3.6 Terminal Deoxynucleotidyl Transferase -- 2.3.7 LMO2 -- 2.3.8 CD20 -- 2.3.9 CD23 -- 2.3.10 Notch1 -- 2.4 Conclusions -- References -- 3: Radiology of Normal Thymus, Thymic Lesions, and Tumors -- 3.1 Introduction -- 3.2 Imaging Modalities -- 3.3 Normal Thymus on Imaging -- 3.4 Thymic Lesions -- 3.5 Imaging Features of Specific Entities |
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3.5.1 Thymic Hyperplasia (Fig. 3.5) -- 3.5.2 Thymic Cyst (Fig. 3.6) -- 3.5.3 Thymic Lymphatic Malformation -- 3.5.4 Dermoid Cyst/Teratoma (Figs. 3.7 and 3.8) -- 3.5.5 Thymic Carcinoid -- 3.5.6 Thymolipoma (Fig. 3.9) -- 3.5.7 Thymoma (Figs. 3.10 and 3.11) -- 3.5.8 Thymic Carcinoma (Figs. 3.12 and 3.13) -- 3.5.9 Lymphoma (Fig. 3.14) -- 3.6 Conclusion -- References -- 4: Surgical Approach to Thymic Lesions -- 4.1 History -- 4.2 Indications for Thymectomy -- 4.3 Surgical Anatomy of Thymus -- 4.4 Principle of Surgery -- 4.5 Surgical Approaches -- 4.6 VATS Thymectomy |
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4.7 Surgeon and Pathologist in Thymic Tumors/Malignancies -- 4.8 Conclusion -- References -- 5: Pathology of Nonneoplastic Thymic Lesions -- 5.1 Thymic Cysts -- 5.2 Primary (Congenital) Thymic Cysts -- 5.3 Secondary (Acquired, Multilocular) Thymic Cysts -- 5.4 Thymic Follicular Hyperplasia (TFH) -- 5.5 Thymic Hyperplasia with Lymphoepithelial Sialadenitis (LESA)-Like Features -- 5.6 True Thymic Hyperplasia -- 5.7 Rebound Hyperplasia of the Thymus -- 5.8 Fibrosing Mediastinitis Including IgG4-Related Disease -- 5.9 Tumoral Cholesterol Granulomas ("Cholesteroloma") of the Thymus |
| Summary |
This book reviews normal thymic structure and covers the histomorphology of benign and malignant tumors and rare lesions of the thymus, with detailed descriptions of over 300 full color photomicrographs accompanied by relevant clinical and radiology photographs and anatomical drawings. It includes chapters on the surgical pathology and cytology of thymic lesions (which is rarely described in the available literature), and all grades and stages of the most common thymic lesions. Written and edited by leading experts on pathology, the book highlights the expanded role of pathologists in patient care for thymic lesions. It will help students to understand thymic cytology and surgical pathology in detail and enable them to answer questions on thymic surgical resections and cytology cases in their pathology post-graduation examination. In addition, the book offers a comprehensive, richly illustrated guide to thymic pathology for clinicians, practicing pathologists, post-graduate residents and students alike |
| Bibliography |
References-6: Gross Pathology of Lesions in the Thymic Region-6.1 Part I: Thymic Hyperplasias (Figs. 6.1 and 6.2)-6.2 Part II: Cystic Lesions of the Thymic Region and Anterior Mediastinum (Figs. 6.3, 6.4, 6.5, 6.6, 6.7, 6.8, 6.9, 6.10, 6.11, 6.12, 6.13, and Table 6.1)-6.3 Part III: Encapsulated, Non-cystic Lesions (Figs. 6.14 and 6.15, 6.16, and 6.17)-6.4 Part IV: Unencapsulated, Solid Masses Containing Multiple Foci of Hemorrhage and Necrosis (Figs. 6.18, 6.19, 6.20, 6.21, 6.22, 6.23, and 6.24) |
| Notes |
6.5 Part V: Solid Masses with a Homogeneous Cut Surface Resembling "Fish Flesh" (Figs. 6.25-6.34) |
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Print version record |
| Subject |
Thymus -- Diseases -- Atlases
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Thymus -- Tumors -- Atlases
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Endocrinology.
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Endocrinology
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Thymus Gland -- pathology
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Thymus Neoplasms
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Thymus -- Tumors
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Thymus -- Diseases
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Pathology
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| Genre/Form |
atlases.
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Scientific atlases
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Atlases.
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Atlas.
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| Form |
Electronic book
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| Author |
Jain, Deepali
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Bishop, Justin A.
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Wick, Mark R., 1952-
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| ISBN |
9789811531644 |
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9811531641 |
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