Introduction to the family -- Background to the study on children with SCID and their families -- Severe combined immunodeficiency, a brief overview -- Effects of early hospitalisation on children -- The effects of isolation and bone marrow transplantation on the child and family -- Children's perceptions of illness and death -- Stressors and coping mechanisms -- Psychosocial effects on the children -- Anger, aggression, and antisocial behaviour in children -- Neurotic and depressive behaviour in children -- Psychosocial effects on the family -- Attachment and alienation -- Post-traumatic stress disorder and children -- Post-traumatic stress disorder in families