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E-book

Title Pediatric obesity : etiology, pathogenesis and treatment / Michael S. Freemark, editor
Edition Second edition
Published Cham, Switzerland : Humana Press, [2018]
©2018

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Description 1 online resource (xxv, 814 pages) : illustrations (chiefly color)
Series Contemporary endocrinology
Contemporary endocrinology (Totowa, N.J.)
Contents Part I: The obesity epidemic: a global perspective. Childhood obesity in the modern age: global trends, determinants, complications, and costs -- Part II: Hormonal and metabolic control of appetite, fat deposition, and energy expenditure. Central control of energy metabolism and hypothalamic obesity -- Gastrointestinal hormones and the control of food intake and energy metabolism -- The gut microbiome and control of weight gain -- Part III: Adipocyte development and function in obesity and insulin resistance. White adipose tissue development and function in children and adolescents: preclinical models -- White adipose tissue accumulation and dysfunction in children with obesity -- Brown adipose tissue and body weight regulation -- Part IV: The genetics of childhood obesity. Monogenic obesity -- Syndromic obesity -- Polygenic obesity -- Part V: Pre- and peri-natal determinants of childhood obesity. Maternal determinants of childhood obesity: maternal obesity, weight gain and smoking -- Fetal and infancy growth -- Intrauterine exposure to maternal diabetes and childhood obesity -- Endocrine disruptors as obesogens -- Part VI: The roles of diet and energy expenditure in obesity pathogenesis and complications. Early feeding practices and development of childhood obesity -- Dietary interventions in the treatment of paediatric obesity -- Vegetarian diets and pediatric obesity -- Energy expenditure in children: the role of neat (non-exercise activity thermogenesis) -- Part VII: Metabolic complications of childhood obesity. Obesity and the endocrine system, part I: pathogenesis of weight gain in endocrine and metabolic disorders -- Obesity and the endocrine system, part II: the effects of childhood obesity on growth and bone maturation, thyroid and adrenal function, sexual development, and bone mineralization -- Metabolomic signatures and metabolic complications in childhood obesity -- Immune function in obesity -- Pathogenesis of insulin resistance and glucose intolerance in childhood obesity -- Youth-onset type 2 diabetes -- Pathogenesis and management of dyslipidemia in obese children -- Fatty liver disease -- Pathogenesis of hypertension and renal disease in obese children -- Sleep-disordered breathing and sleep duration in childhood obesity -- Pediatric metabolic syndrome: long-term risks for type 2 diabetes and cardiovascular disease -- Childhood obesity, atherogenesis, and adult cardiovascular disease -- Childhood obesity and cognitive function -- Part VIII: Treatment of childhood obesity: lifestyle intervention. Family-based behavioral interventions for childhood obesity -- Exercise and childhood obesity -- School- and community-based interventions for childhood obesity -- Part IX: Pharmacotherapy and bariatric surgery for obesity and co-morbidities. Role of pharmacotherapy in the treatment of pediatric obesity and its comorbidities -- Pathogenesis and management of adiposity and insulin resistance in polycystic ovary syndrome (PCOS) -- Prevention and treatment of obesity and metabolic dysfunction in children with major behavioral disorders: second-generation antipsychotics -- Bariatric surgery in adolescents -- Part X: Challenges to long-term success. The role of the primary care provider in long-term counseling: establishing a therapeutic alliance with the child and family -- The sociocultural context for obesity prevention and treatment in children and adolescents: influences of ethnicity and gender -- Part XI: The future of childhood obesity in the global marketplace -- Fast-food value chains and childhood obesity: a global perspective -- Why we need local, state, and national policy-based approaches to improve children's nutrition in the United States
Summary "This second edition of Freemark's text embodies all of the strengths of the original work but is deeper and broader in scope, with new chapters on emerging themes including metabolomics, genomics, and the roles of gastrointestinal hormones, the microbiome, brown adipose tissue, and endocrine disruptors in the pathogenesis of childhood obesity. Reviews of the effects of weight excess on cognitive performance and immune function complement detailed analyses of the biochemical and molecular pathways controlling the development of childhood adiposity and metabolic disease. Critical assessments of nutritional interventions (including new chapters on infant feeding practices and vegetarian diets) and superb reviews of behavioral counseling, pharmacotherapy, and bariatric surgery provide practical guidance for the management of overweight children. Penetrating analyses of the obesity epidemic in its social, cultural, economic, and political contexts highlight challenges and opportunities for obesity prevention and community action. The perspective is international in scope and reflects the expertise and experience of many of the leading figures in the field"--Publisher's description
Bibliography Includes bibliographical references and index
Notes Online resource; title from electronic title page (SpringerLink, viewed May 31, 2018)
Subject Obesity in children -- Genetic aspects
Obesity in children -- Social aspects
Obesity in children -- Treatment
Pediatric Obesity -- etiology
Pediatric Obesity -- therapy
MEDICAL -- Gynecology & Obstetrics.
Obesity in children -- Treatment
Form Electronic book
Author Freemark, Michael, editor.
ISBN 9783319681924
3319681923